Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6204613 | 0.80 | SLC1A3 (0.43) | ALDH1A1TDP1MAPK1KMT2ASLC6A2 | |
| SCHEMBL4697046 | 0.80 | LMNA (0.41) | ALDH1A1POLBKMT2ASLC6A2SLC6A3 | |
| SCHEMBL4700964 | 0.79 | LMNA (0.39) | ALDH1A1MAPK1GAANPSR1POLB | |
| SCHEMBL4699725 | 0.78 | LMNA (0.39) | ALDH1A1MAPK1GAANPSR1POLB | |
| SCHEMBL4699470 | 0.77 | LMNA (0.38) | ALDH1A1MAPK1GAANPSR1POLB | |
| Hydrochloric Acid SCHEMBL10871469 | 0.74 | ALDH1A1 (0.50) | ALDH1A1TDP1MAPK1GAAKMT2A | |
| SCHEMBL4699779 | 0.74 | PRKCA (0.30) | — | |
| SCHEMBL28875175 | 0.72 | TDP1 (0.68) | ALDH1A1TDP1MAPK1GAAKMT2A | |
| SCHEMBL51601 | 0.72 | TDP1 (0.68) | ALDH1A1TDP1MAPK1GAAKMT2A | |
| SCHEMBL1713120 | 0.69 | TDP1 (0.50) | ALDH1A1TDP1MAPK1GAANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1919859-A2 | ACYLOXYALKYL CARBAMATE PRODRUGS OF TRANEXAMIC ACID, METHODS OF SYNTHESIS AND USE | Xenoport, Inc. (US) | 2008-05-14 | — | — | EP | claimed |
| WO-2007002013-A2 | ACYLOXYALKYL CARBAMATE PRODRUGS OF TRANEXAMIC ACID, METHODS OF SYNTHESIS AND USE | XENOPORT, INC. (US) | 2007-01-04 | — | — | WO | claimed |