Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2075017 | 0.88 | GPR119 (0.37) | — | |
| SCHEMBL2074777 | 0.86 | GPR119 (0.37) | — | |
| SCHEMBL2076532 | 0.85 | EPHX1 (0.37) | — | |
| SCHEMBL2074413 | 0.83 | GPR119 (0.38) | — | |
| SCHEMBL6027740 | 0.77 | CXCR2 (0.32) | HTR2AHTR2CHTR2B | |
| SCHEMBL4696960 | 0.76 | PDK2 (0.36) | — | |
| SCHEMBL2076219 | 0.75 | SCN4A (0.31) | — | |
| SCHEMBL2076465 | 0.75 | UCHL1 (0.31) | — | |
| SCHEMBL2075265 | 0.75 | GPR119 (0.33) | — | |
| SCHEMBL16036419 | 0.72 | P2RX7 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1905774-B1 | Fused heterocyclic compounds as serotonin receptor modulators | JANSSEN PHARMACEUTICA NV (BE) | 2013-02-20 | — | — | EP | disclosed |
| EP-1944306-A1 | Fused heterocyclic compounds as serotonin receptor modulators | Janssen Pharmaceutica, N.V. (BE) | 2008-07-16 | — | — | EP | disclosed |
| EP-1905774-A1 | Fused heterocyclic compounds as serotonin receptor modulators | Janssen Pharmaceutica, N.V. (BE) | 2008-04-02 | — | — | EP | disclosed |