Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6451749 | 0.85 | CYP3A4 (0.46) | TSHRCES2CES1RIPK1HTT | |
| SCHEMBL9337268 | 0.83 | TSHR (0.40) | TSHRCES2CES1RIPK1HTT | |
| SCHEMBL9794572 | 0.81 | MLYCD (0.43) | TSHRCES2CES1RIPK1HTT | |
| SCHEMBL9363884 | 0.81 | RIPK1 (0.46) | TSHRCES2CES1RIPK1HTT | |
| SCHEMBL9835586 | 0.76 | MAPT (0.37) | TSHRCES2CES1RIPK1HTT | |
| SCHEMBL11428259 | 0.75 | HTT (0.38) | TSHRCES2CES1RIPK1HTT | |
| SCHEMBL4699159 | 0.73 | PSEN1 (0.39) | TSHRCES2CES1HTTDDB1 | |
| SCHEMBL9359593 | 0.73 | CYP3A4 (0.43) | RIPK1CYP3A4ALDH1A1 | |
| SCHEMBL5716046 | 0.72 | CYP3A4 (0.46) | CES2CES1RIPK1HTTDDB1 | |
| SCHEMBL9678771 | 0.72 | PTK2 (0.41) | HTTALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0974587-B1 | 1-SUBSTITUTED 4-CARBAMOYL-1,2,4-TRIAZOL-5-ONE DERIVATIVES AND HERBICIDE | HOKKO CHEM IND CO (JP) | 2008-04-23 | — | — | EP | disclosed |
| US-6077814-A | LOW PHYTOTOXICITY TO THE CROP PLANTS; SELECTIVE ACTIVITY | HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) | 2000-06-20 | — | — | US | disclosed |
| EP-0974587-A1 | 1-SUBSTITUTED 4-CARBAMOYL-1,2,4-TRIAZOL-5-ONE DERIVATIVES AND HERBICIDE | HOKKO CHEMICAL INDUSTRY CO. LTD. (JP) | 2000-01-26 | — | — | EP | disclosed |