Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | RXFP3 | Q9NSD7 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | MPO | P05164 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | HTR1D | P28221 | 1/20 | 0.46 |
| ▸ | HTR1B | P28222 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4699037 | 0.83 | ADORA2A (0.51) | ADORA2ARAB9AMEN1KMT2AMAPT | |
| SCHEMBL4700168 | 0.79 | ADORA2A (0.47) | ADORA2ARAB9AMEN1KMT2AMAPT | |
| SCHEMBL2799588 | 0.78 | MC5R (0.64) | ADORA2ARAB9AMEN1KMT2AMAPT | |
| SCHEMBL4700992 | 0.77 | RXFP3 (0.66) | ADORA2ARAB9AMEN1KMT2AMAPT | |
| SCHEMBL9670836 | 0.77 | FAAH (0.54) | RAB9AMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL4701665 | 0.73 | ALDH1A1 (0.49) | MAPTL3MBTL1SMN1; SMN2RXFP3LMNA | |
| SCHEMBL4701255 | 0.73 | RXFP3 (0.84) | RAB9AMAPTRXFP3CYP1A2CYP3A4 | |
| SCHEMBL4699822 | 0.72 | MAPT (0.63) | RAB9AMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL25029869 | 0.72 | MEN1 (0.56) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL578644 | 0.72 | MEN1 (0.56) | MEN1KMT2AMAPTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7153881-B2 | Compounds acting as melanocortin receptor ligands | ACURE PHARMA AB (SE) | 2006-12-26 | — | — | US | claimed |
| EP-1309544-B1 | COMPOUNDS ACTING AS MELANOCORTIN RECEPTOR LIGANDS | ACURE PHARMA AB (SE) | 2008-11-05 | — | — | EP | disclosed |
| US-7153881-B2 | Compounds acting as melanocortin receptor ligands | ACURE PHARMA AB (SE) | 2006-12-26 | — | — | US | disclosed |