Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | RXFP3 | Q9NSD7 | 1/20 | 0.43 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4697190 | 0.83 | HTR6 (0.55) | ALDH1A1HTTKDM4EPOLBHTR6 | |
| SCHEMBL4701026 | 0.74 | HTR1A (0.48) | HTR6SMN1; SMN2RXFP3 | |
| SCHEMBL4699091 | 0.73 | RXFP3 (0.64) | HTR6RXFP3 | |
| SCHEMBL6498354 | 0.70 | MAPT (0.43) | LMNAMAPTGAAL3MBTL1 | |
| SCHEMBL19087996 | 0.70 | ALDH1A1 (0.63) | ALDH1A1TSHRHTTKDM4EPOLB | |
| SCHEMBL5207930 | 0.69 | EGFR (0.66) | ALDH1A1TSHRHTTKDM4EPOLB | |
| SCHEMBL1424220 | 0.68 | ALDH1A1 (0.69) | ALDH1A1TSHRHTTKDM4EPOLB | |
| SCHEMBL7844388 | 0.68 | ALDH1A1 (1.00) | ALDH1A1TSHRHTTKDM4EPOLB | |
| SCHEMBL29415611 | 0.68 | ALDH1A1 (0.69) | ALDH1A1TSHRHTTKDM4EPOLB | |
| SCHEMBL28687424 | 0.67 | KDM4E (0.67) | ALDH1A1TSHRHTTKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7153881-B2 | Compounds acting as melanocortin receptor ligands | ACURE PHARMA AB (SE) | 2006-12-26 | — | — | US | claimed |
| EP-1309544-B1 | COMPOUNDS ACTING AS MELANOCORTIN RECEPTOR LIGANDS | ACURE PHARMA AB (SE) | 2008-11-05 | — | — | EP | disclosed |
| US-7153881-B2 | Compounds acting as melanocortin receptor ligands | ACURE PHARMA AB (SE) | 2006-12-26 | — | — | US | disclosed |