SCHEMBL469795

SCHEMBL469795

NCN(CN)c1nc(N(CN)CN)nc(N(CN)CN)n1

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
LMNA P02545 1/20 0.32
CYP1A2 P05177 1/20 0.32
THRB P10828 1/20 0.32
BLM P54132 1/20 0.32
CREBBP Q92793 1/20 0.32
HSD17B10 Q99714 1/20 0.32
MAPT P10636 2/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL428282 0.86 TSHR (0.46) TSHRTDP1MAPTSMN1; SMN2
SCHEMBL469796 0.73 MAPT (0.38) TSHRTDP1MAPTSMN1; SMN2
SCHEMBL16558118 0.72 TSHR (0.36) TSHRTDP1MAPT
SCHEMBL469846 0.69 MAPT (0.35) TSHRLMNABLMMAPTSMN1; SMN2
SCHEMBL2741119 0.64 TDP1 (0.64) TSHRTDP1LMNACYP1A2THRB
Ammonia Solution, Strong SCHEMBL9875109 0.62 SLC29A1 (0.33) TSHRTDP1LMNACYP1A2THRB
SCHEMBL62454 0.61 MAPT (0.41) CYP1A2MAPT
SCHEMBL2338559 0.61 MAPT (0.66) TSHRTDP1MAPTSMN1; SMN2
Methyl Alcohol SCHEMBL7196036 0.60 SLC29A1 (0.37) TSHRTDP1LMNACYP1A2THRB
SCHEMBL469797 0.58 TSHR (0.44) TSHRTDP1MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9221960-B2 Multifunctional melamine epoxy resins, methylols and amines EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2015-12-29 US disclosed
US-20150073103-A1 MULTIFUNCTIONAL MELAMINE EPOXY RESINS, METHYLOLS AND AMINES CRESTLINE DIRECT FINANCE, L.P. 2015-03-12 US disclosed
US-8911858-B2 Multifunctional melamine epoxy resins, methylols and amines EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2014-12-16 US disclosed
US-8911858-B2 Multifunctional melamine epoxy resins, methylols and amines EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2014-12-16 US disclosed
US-20140179838-A1 MULTIFUNCTIONAL MELAMINE EPOXY RESINS, METHYLOLS AND AMINES EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2014-06-26 US disclosed
US-20140179838-A1 MULTIFUNCTIONAL MELAMINE EPOXY RESINS, METHYLOLS AND AMINES EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2014-06-26 US disclosed
WO-2014070155-A1 MULTIFUNCTIONAL MELAMINE EPOXY RESINS, METHYLOLS AND AMINES EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2014-05-08 WO disclosed
WO-2012033607-A1 METHODS OF REMOVING CARBON DIOXIDE AND SORBENTS FOR SAME BATTELLE ENERGY ALLIANCE, LLC (US) 2012-03-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140179838-A1 MULTIFUNCTIONAL MELAMINE EPOXY RESINS, METHYLOLS AND AMINES PNMT, HNMT, NNMT TSHR 2435/4885TDP1 2104/4885LMNA 1209/4885
US-20150073103-A1 MULTIFUNCTIONAL MELAMINE EPOXY RESINS, METHYLOLS AND AMINES PNMT, HNMT, NNMT TSHR 2435/4885TDP1 2104/4885LMNA 1209/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.