Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CTSA | P10619 | 8/20 | 0.42 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.40 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.39 |
| ▸ | LCK | P06239 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL687794 | 0.90 | MEN1 (0.45) | ALDH1A1KDM4ECTSAITGB1ITGA4 | |
| SCHEMBL688357 | 0.84 | POLB (0.41) | ALDH1A1KDM4ECTSAPTGER3MAPT | |
| SCHEMBL687381 | 0.84 | CTSA (0.47) | ALDH1A1KDM4ECTSAPTGER3P2RY14 | |
| SCHEMBL687522 | 0.83 | CTSA (0.44) | ALDH1A1KDM4ECTSAPTGER3MAPT | |
| SCHEMBL687932 | 0.82 | EGLN1 (0.44) | ALDH1A1KDM4ECTSAPTGER3P2RY14 | |
| SCHEMBL688110 | 0.82 | MEN1 (0.49) | ALDH1A1KDM4ECTSAMAPTITGB1 | |
| SCHEMBL687488 | 0.81 | MAPT (0.51) | ALDH1A1KDM4ECTSAPTGER3P2RY14 | |
| SCHEMBL686919 | 0.81 | GAA (0.45) | ALDH1A1KDM4EL3MBTL1CTSAMAPT | |
| SCHEMBL686620 | 0.80 | PTGER3 (0.50) | ALDH1A1KDM4ECTSAPTGER3MAPT | |
| SCHEMBL687486 | 0.80 | ALDH1A1 (0.41) | ALDH1A1KDM4ECTSAPTGER3ITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1176956-B1 | CARBOXYLIC ACID DERIVATIVES THAT INHIBIT THE BINDING OF INTEGRINS TO THEIR RECEPTORS | ENCYSIVE PHARMACEUTICALS INC (US) | 2008-01-09 | — | — | EP | disclosed |