Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4702925 | 0.87 | NPC1 (0.44) | SMN1; SMN2RAB9ANPC1TRPV1MAPT | |
| SCHEMBL4700184 | 0.74 | RAB9A (0.43) | SMN1; SMN2RAB9ANPC1SIGMAR1MAPT | |
| SCHEMBL16993706 | 0.73 | PLAU (0.49) | SMN1; SMN2SIGMAR1MAPTALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL5703010 | 0.72 | PLAU (0.47) | SMN1; SMN2SIGMAR1MAPTALDH1A1MEN1 | |
| SCHEMBL4701252 | 0.69 | NPC1 (0.49) | SMN1; SMN2RAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL13584139 | 0.69 | NPC1 (0.59) | SMN1; SMN2RAB9ANPC1TAAR1CA12 | |
| SCHEMBL4698438 | 0.68 | LMNA (0.51) | SMN1; SMN2MAPTMEN1KMT2AHTT | |
| SCHEMBL3926232 | 0.67 | NPC1 (0.57) | SMN1; SMN2RAB9ANPC1TAAR1CA12 | |
| Hydrochloric Acid SCHEMBL13585003 | 0.67 | NPC1 (0.57) | SMN1; SMN2RAB9ANPC1TAAR1CA12 | |
| SCHEMBL3916719 | 0.66 | NPC1 (0.55) | SMN1; SMN2RAB9ANPC1TAAR1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1309544-B1 | COMPOUNDS ACTING AS MELANOCORTIN RECEPTOR LIGANDS | ACURE PHARMA AB (SE) | 2008-11-05 | — | — | EP | claimed |
| US-7153881-B2 | Compounds acting as melanocortin receptor ligands | ACURE PHARMA AB (SE) | 2006-12-26 | — | — | US | claimed |
| EP-1309544-B1 | COMPOUNDS ACTING AS MELANOCORTIN RECEPTOR LIGANDS | ACURE PHARMA AB (SE) | 2008-11-05 | — | — | EP | disclosed |