Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | BRS3 | P32247 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6026754 | 0.83 | IDO1 (0.41) | KMT2AMEN1ALDH1A1MAPTCYP3A4 | |
| SCHEMBL4700989 | 0.83 | IDO1 (0.48) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL4699819 | 0.81 | KMT2A (0.48) | KMT2AMEN1MAPTTSHRKDM4E | |
| SCHEMBL4698347 | 0.76 | STING1 (0.41) | NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL4699088 | 0.75 | MTNR1A (0.53) | POLBKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL4697802 | 0.71 | MEN1 (0.53) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL4701251 | 0.71 | RAB9A (0.55) | NPC1RAB9APOLBKMT2AMEN1 | |
| SCHEMBL4698441 | 0.69 | SMN1; SMN2 (0.39) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL12049633 | 0.67 | MEN1 (0.76) | NPC1RAB9APOLBKMT2AMEN1 | |
| SCHEMBL17887852 | 0.67 | EPHX1 (0.62) | NPC1RAB9AKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7153881-B2 | Compounds acting as melanocortin receptor ligands | ACURE PHARMA AB (SE) | 2006-12-26 | — | — | US | claimed |
| EP-1309544-B1 | COMPOUNDS ACTING AS MELANOCORTIN RECEPTOR LIGANDS | ACURE PHARMA AB (SE) | 2008-11-05 | — | — | EP | disclosed |
| US-7153881-B2 | Compounds acting as melanocortin receptor ligands | ACURE PHARMA AB (SE) | 2006-12-26 | — | — | US | disclosed |