SCHEMBL4698865

SCHEMBL4698865

CN(C)[CH][CH]c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RELA Q04206 1/20 0.43
ALDH1A1 P00352 4/20 0.38
TSHR P16473 3/20 0.38
GRM5 P41594 1/20 0.38
MAOB P27338 1/20 0.38
CYP2A6 P11509 1/20 0.38
LMNA P02545 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
CHAT P28329 2/20 0.34
RECQL P46063 1/20 0.34
AKR1C3 P42330 1/20 0.33
TRPA1 O75762 1/20 0.33
GLA P06280 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
KCNN4 O15554 1/20 0.33
NPC1 O15118 1/20 0.32
MAPT P10636 1/20 0.32
CASP3 P42574 1/20 0.32
RAB9A P51151 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28194304 0.75 MAOB (0.59) RELAALDH1A1GRM5MAOBLMNA
(Z)-1,2-Diphenylethene SCHEMBL817116 0.73 ALDH1A1 (0.53) ALDH1A1TSHRMAOBCYP2A6LMNA
SCHEMBL169417 0.72 RELA (0.46) RELAALDH1A1TSHRGRM5MAOB
(Z)-1,2-Diphenylethene SCHEMBL27459562 0.69 RELA (0.68) RELAALDH1A1GRM5MAOBCHAT
Trimethylammonium SCHEMBL27686011 0.69 RELA (0.48) RELAALDH1A1TSHRGRM5MAOB
SCHEMBL3949316 0.69
SCHEMBL952396 0.68 RELA (0.54) RELAALDH1A1GRM5MAOBLMNA
SCHEMBL81307 0.68 RELA (0.54) RELAALDH1A1GRM5MAOBLMNA
SCHEMBL6330348 0.67 MAOB (0.56) ALDH1A1TSHRMAOBCYP2A6LMNA
SCHEMBL6330351 0.67 MAOB (0.56) ALDH1A1TSHRMAOBCYP2A6LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1737868-B1 STEREOSELECTIVE METHOD FOR THE PRODUCTION OF CLOPIDOGREL RATIOPHARM GMBH (DE) 2008-02-27 EP disclosed