Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | MC1R | Q01726 | 4/20 | 0.45 |
| ▸ | MC5R | P33032 | 3/20 | 0.45 |
| ▸ | MC3R | P41968 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6026754 | 0.85 | IDO1 (0.41) | KMT2AMEN1MAPTIDO1MC1R | |
| SCHEMBL4700989 | 0.85 | IDO1 (0.48) | KMT2AMEN1IDO1MC1RMC5R | |
| SCHEMBL4701252 | 0.81 | NPC1 (0.49) | KMT2AMEN1MAPTLMNACYP3A4 | |
| SCHEMBL4700165 | 0.78 | MEN1 (0.45) | KMT2AMEN1MAPTIDO1MC1R | |
| SCHEMBL4698347 | 0.78 | STING1 (0.41) | KMT2AMEN1IDO1GPR84 | |
| SCHEMBL21562558 | 0.75 | KMT2A (0.53) | KMT2AMEN1MAPTIDO1MC1R | |
| SCHEMBL4697802 | 0.71 | MEN1 (0.53) | KMT2AMEN1IDO1LMNAHTT | |
| SCHEMBL6245322 | 0.70 | MEN1 (0.55) | KMT2AMEN1MAPTIDO1MC1R | |
| SCHEMBL11629345 | 0.70 | KMT2A (0.55) | KMT2AMEN1MAPTIDO1MC1R | |
| SCHEMBL6025185 | 0.69 | MAPT (0.56) | KMT2AMEN1MAPTLMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7153881-B2 | Compounds acting as melanocortin receptor ligands | ACURE PHARMA AB (SE) | 2006-12-26 | — | — | US | claimed |
| EP-1309544-B1 | COMPOUNDS ACTING AS MELANOCORTIN RECEPTOR LIGANDS | ACURE PHARMA AB (SE) | 2008-11-05 | — | — | EP | disclosed |
| US-7153881-B2 | Compounds acting as melanocortin receptor ligands | ACURE PHARMA AB (SE) | 2006-12-26 | — | — | US | disclosed |