Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 13/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6026754 | 0.89 | IDO1 (0.41) | IDO1GPR84MEN1KMT2ANR4A2 | |
| SCHEMBL4699819 | 0.78 | KMT2A (0.48) | IDO1GPR84MEN1KMT2A | |
| SCHEMBL4701252 | 0.76 | NPC1 (0.49) | MEN1NPC1RAB9AKMT2A | |
| SCHEMBL22234314 | 0.75 | STING1 (0.48) | STING1IDO1GPR84 | |
| SCHEMBL4700989 | 0.73 | IDO1 (0.48) | IDO1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL8065238 | 0.71 | STING1 (0.50) | STING1IDO1GPR84MEN1KMT2A | |
| Iodide SCHEMBL9093454 | 0.70 | STING1 (0.49) | STING1IDO1GPR84NR4A2CREBBP | |
| SCHEMBL384965 | 0.70 | STING1 (0.63) | STING1GPR84MEN1NPC1RAB9A | |
| SCHEMBL9011712 | 0.69 | STING1 (0.49) | STING1GPR84MEN1KMT2ANR4A2 | |
| SCHEMBL4506896 | 0.68 | STING1 (0.50) | STING1GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7153881-B2 | Compounds acting as melanocortin receptor ligands | ACURE PHARMA AB (SE) | 2006-12-26 | — | — | US | claimed |
| EP-1309544-B1 | COMPOUNDS ACTING AS MELANOCORTIN RECEPTOR LIGANDS | ACURE PHARMA AB (SE) | 2008-11-05 | — | — | EP | disclosed |
| US-7153881-B2 | Compounds acting as melanocortin receptor ligands | ACURE PHARMA AB (SE) | 2006-12-26 | — | — | US | disclosed |