Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.35 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | MC5R | P33032 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4698347 | 0.89 | STING1 (0.41) | IDO1GPR84NR4A2CREBBPMEN1 | |
| SCHEMBL4699819 | 0.85 | KMT2A (0.48) | IDO1GPR84MEN1KMT2ACYP3A4 | |
| SCHEMBL4701252 | 0.83 | NPC1 (0.49) | MEN1KMT2ACYP3A4MAPTTDP1 | |
| SCHEMBL4700989 | 0.80 | IDO1 (0.48) | IDO1MEN1KMT2AALDH1A1HTT | |
| SCHEMBL4703485 | 0.72 | IDO1 (0.45) | IDO1GPR84ATMMEN1KMT2A | |
| SCHEMBL1849779 | 0.65 | NPC1 (0.51) | GPR84ATMMEN1KMT2ACYP3A4 | |
| SCHEMBL15689981 | 0.65 | HPGD (0.46) | GPR84ATMMEN1KMT2ACYP3A4 | |
| SCHEMBL9011712 | 0.64 | STING1 (0.49) | GPR84ATMNR4A2CREBBPMEN1 | |
| SCHEMBL22234314 | 0.62 | STING1 (0.48) | IDO1GPR84ATMMAPTALDH1A1 | |
| SCHEMBL1007651 | 0.62 | GPR84 (0.56) | GPR84ATMNR4A2CREBBPMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7153881-B2 | Compounds acting as melanocortin receptor ligands | ACURE PHARMA AB (SE) | 2006-12-26 | — | — | US | claimed |
| US-7153881-B2 | Compounds acting as melanocortin receptor ligands | ACURE PHARMA AB (SE) | 2006-12-26 | — | — | US | disclosed |