Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | AANAT | Q16613 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MC5R | P33032 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4699819 | 0.85 | KMT2A (0.48) | IDO1MEN1KMT2ALMNACYP1A2 | |
| SCHEMBL4701252 | 0.83 | NPC1 (0.49) | MEN1KMT2ALMNACYP1A2PKM | |
| SCHEMBL4699033 | 0.81 | IDO1 (0.45) | IDO1MEN1KMT2ALMNACYP1A2 | |
| SCHEMBL6026754 | 0.80 | IDO1 (0.41) | IDO1MEN1KMT2AALDH1A1HTT | |
| SCHEMBL4697802 | 0.76 | MEN1 (0.53) | IDO1MEN1KMT2ALMNACYP1A2 | |
| SCHEMBL20258567 | 0.74 | IDO1 (0.57) | IDO1MEN1KMT2ALMNACYP1A2 | |
| SCHEMBL4698347 | 0.73 | STING1 (0.41) | IDO1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL13645785 | 0.73 | MTNR1A (0.69) | IDO1MEN1KMT2ALMNACYP1A2 | |
| SCHEMBL7005718 | 0.71 | HTR2A (0.71) | MEN1KMT2ACYP1A2KDM4EALDH1A1 | |
| SCHEMBL7004146 | 0.71 | HTR2A (0.71) | MEN1KMT2ACYP1A2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7153881-B2 | Compounds acting as melanocortin receptor ligands | ACURE PHARMA AB (SE) | 2006-12-26 | — | — | US | claimed |
| EP-1309544-B1 | COMPOUNDS ACTING AS MELANOCORTIN RECEPTOR LIGANDS | ACURE PHARMA AB (SE) | 2008-11-05 | — | — | EP | disclosed |
| US-7153881-B2 | Compounds acting as melanocortin receptor ligands | ACURE PHARMA AB (SE) | 2006-12-26 | — | — | US | disclosed |