SCHEMBL470032

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL27926219	0.87	SMN1; SMN2 (0.37)	SMN1; SMN2ALDH1A1POLBTDP1KDM4E
	SCHEMBL15086656	0.87	SLC34A1 (0.42)	SMN1; SMN2ALDH1A1POLBTDP1KDM4E
	SCHEMBL15064006	0.83	PTGS2 (0.42)	ALDH1A1POLBTDP1HPGDPTGS2
	SCHEMBL15334400	0.81	HPGD (0.30)	ALDH1A1HPGD
	SCHEMBL12482118	0.78	HPGD (0.32)	SMN1; SMN2ALDH1A1HPGD
	SCHEMBL466412	0.78	MAPT (0.36)	SMN1; SMN2ALDH1A1POLBTP53MAPT
	SCHEMBL15341141	0.77	SMN1; SMN2 (0.35)	SMN1; SMN2ALDH1A1HPGD
	SCHEMBL15344234	0.76	—	—
	SCHEMBL12481542	0.76	HPGD (0.30)	ALDH1A1HPGD
	SCHEMBL12481552	0.76	CDK8 (0.33)	ALDH1A1POLBKDM4EMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.