SCHEMBL466412

SCHEMBL466412

CCc1cc(C)cc(CC)c1-c1c(O)c(C)nn(C)c1=O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.36
LMNA P02545 1/20 0.36
TP53 P04637 1/20 0.36
CDK8 P49336 1/20 0.34
ACVR1 Q04771 1/20 0.34
POLB P06746 1/20 0.32
CRHR1 P34998 1/20 0.32
PDE4A P27815 1/20 0.32
PDE4B Q07343 1/20 0.32
PDE4C Q08493 1/20 0.32
PDE4D Q08499 1/20 0.32
HPGD P15428 2/20 0.32
ALDH1A1 P00352 1/20 0.31
GAA P10253 1/20 0.31
MAPK1 P28482 1/20 0.31
PPARG P37231 1/20 0.31
HTT P42858 1/20 0.31
MAPK10 P53779 1/20 0.31
NCOA2 Q15596 1/20 0.31
RXFP1 Q9HBX9 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16642353 0.93 CRHR1 (0.38) MAPTLMNATP53CDK8ACVR1
SCHEMBL10288222 0.90 LMNA (0.33) MAPTLMNATP53CDK8ACVR1
SCHEMBL510530 0.90 MAPK8 (0.36) MAPTLMNATP53CDK8ACVR1
SCHEMBL12482118 0.88 HPGD (0.32) HPGDALDH1A1GAAMAPK1PPARG
SCHEMBL15341141 0.87 SMN1; SMN2 (0.35) LMNACRHR1HPGDALDH1A1GAA
SCHEMBL27907825 0.86 CDK8 (0.34) MAPTCDK8ACVR1POLBHPGD
SCHEMBL15334400 0.85 HPGD (0.30) HPGDALDH1A1GAAMAPK1PPARG
SCHEMBL12481542 0.85 HPGD (0.30) HPGDALDH1A1GAAMAPK1PPARG
SCHEMBL12481552 0.85 CDK8 (0.33) MAPTLMNACDK8ACVR1POLB
SCHEMBL12481930 0.85 HPGD (0.30) HPGDALDH1A1GAAMAPK1PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 302 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119504550-A Pyrrolidone herbicide 河南蓝创作物科学有限公司 2025-02-25 CN claimed
EP-4096400-A1 LIQUID SULFONYLUREA COMPOSITIONS FMC Agricultural Caribe Industries Ltd. (BM) 2022-12-07 EP claimed
WO-2021152391-A1 LIQUID SULFONYLUREA COMPOSITIONS FMC AGRICULTURAL CARIBE INDUSTRIES LTD. (BM) 2021-08-05 WO claimed
WO-2019030088-A1 HERBICIDAL MIXTURES COMPRISING L-GLUFOSINATE AND THEIR USE IN CEREAL CULTURES BASF SE (DE) 2019-02-14 WO claimed
US-20260098020-A1 HERBICIDAL PYRIMIDINYLMETHYL-SUBSTITUTED 1,2,4-TRIAZOLES FMC CORP (US) 2026-04-09 US disclosed
EP-4714942-A1 SUBSTITUTED HALOALKYL SULFONANILIDE HERBICIDES FMC Corporation (US) 2026-03-25 EP disclosed
US-12552752-B2 Atropisomers of pyridazinone derivatives as herbicides FMC CORPORATION (US) 2026-02-17 US disclosed
EP-4683908-A1 SUBSTITUTED OXAZOLIDINONES AND IMIDAZOLINONES AS HERBICIDES FMC Corporation (US) 2026-01-28 EP disclosed
EP-4188093-B9 SUBSTITUTED HALOALKYL SULFONANILIDE HERBICIDES FMC CORP (US) 2025-12-03 EP disclosed
US-12435044-B2 Pyridazinone herbicides and pyridazinone intermediates used to prepare a herbicide FMC CORPORATION (US) 2025-10-07 US disclosed
EP-3599868-B1 HERBICIDAL MIXTURE, COMPOSITION AND METHOD FMC CORP (US) 2025-09-24 EP disclosed
EP-4188093-B1 SUBSTITUTED HALOALKYL SULFONANILIDE HERBICIDES FMC CORP (US) 2025-09-03 EP disclosed
US-20110319266-A1 HERBICIDAL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-29 US disclosed
US-20100298142-A1 HERBICIDAL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-11-25 US disclosed
US-20100248964-A1 HERBICIDAL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-09-30 US disclosed
WO-2010104217-A1 PYRIDAZINONE COMPOUND AND USE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-09-16 WO disclosed
WO-2010104216-A1 HERBICIDAL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-09-16 WO disclosed
US-20100210462-A1 HERBICIDAL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-08-19 US disclosed
EP-1996557-B1 PYRIDAZINONE COMPOUND AND USE THEREOF AS HERBICIDES SUMITOMO CHEMICAL CO (JP) 2010-03-03 EP disclosed
US-20090111696-A1 Pyridazinone Compound and Use Thereof as herbicides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-04-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110319266-A1 HERBICIDAL COMPOSITION DDT, EGLN1, ELF3 MAPT 3582/4885LMNA 2493/4885TP53 4760/4885
US-20100248964-A1 HERBICIDAL COMPOSITION CHRM2, CHRM1, WEE1 MAPT 4336/4885LMNA 3541/4885TP53 4440/4885
US-20100210462-A1 HERBICIDAL COMPOSITION WEE1, WEE2, H1-3 MAPT 4413/4885LMNA 3560/4885TP53 4170/4885
US-12435044-B2 Pyridazinone herbicides and pyridazinone intermediates used to prepare a herbicide CBR3, CBR1, CYP4F3 MAPT 4763/4885LMNA 2149/4885TP53 2308/4885
US-12552752-B2 Atropisomers of pyridazinone derivatives as herbicides CBR3, TDO2, FOXO3 MAPT 3434/4885LMNA 4256/4885TP53 4574/4885
US-20260098020-A1 HERBICIDAL PYRIMIDINYLMETHYL-SUBSTITUTED 1,2,4-TRIAZOLES CBR3, CBR1, CNPY3 MAPT 4769/4885LMNA 2391/4885TP53 3593/4885
US-20090111696-A1 Pyridazinone Compound and Use Thereof as herbicides PDXK, DDT, PLPBP MAPT 3414/4885LMNA 3335/4885TP53 4725/4885
US-20100298142-A1 HERBICIDAL COMPOSITION CYP2W1, WEE2, CYP2J2 MAPT 4587/4885LMNA 3206/4885TP53 4161/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.