Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 5/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4757562 | 0.85 | SMN1; SMN2 (0.39) | CRHR1 | |
| SCHEMBL4702271 | 0.83 | CRHR1 (0.39) | CRHR1 | |
| SCHEMBL4701270 | 0.80 | CHRM2 (0.39) | CRHR1 | |
| SCHEMBL4698855 | 0.79 | CRHR1 (0.44) | DRD4CRHR1 | |
| SCHEMBL4702341 | 0.78 | CRHR1 (0.40) | CRHR1 | |
| Hydrochloric Acid SCHEMBL4697950 | 0.78 | CRHR1 (0.44) | CRHR1 | |
| SCHEMBL4700164 | 0.78 | SCN8A (0.44) | CRHR1 | |
| SCHEMBL4702626 | 0.78 | HEXA (0.43) | — | |
| Trifluoroacetic Acid SCHEMBL4703706 | 0.76 | MEN1 (0.40) | CRHR1 | |
| SCHEMBL6025193 | 0.73 | CRHR1 (0.42) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1569911-B1 | INDAZOLE DERIVATIVES AS CRF ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2008-07-02 | — | — | EP | claimed |