Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 3/20 | 0.39 |
| ▸ | SCN8A | Q9UQD0 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 4/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4703706 | 0.92 | MEN1 (0.40) | CRHR1SCN8AMEN1KMT2APOLB | |
| SCHEMBL4700164 | 0.89 | SCN8A (0.44) | CRHR1SCN8ANSD2 | |
| SCHEMBL4702626 | 0.86 | HEXA (0.43) | POLB | |
| SCHEMBL4701270 | 0.84 | CHRM2 (0.39) | CRHR1MEN1KMT2APOLB | |
| SCHEMBL4757562 | 0.84 | SMN1; SMN2 (0.39) | CRHR1MEN1KMT2A | |
| SCHEMBL4698855 | 0.84 | CRHR1 (0.44) | CRHR1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4697950 | 0.83 | CRHR1 (0.44) | CRHR1MEN1KMT2A | |
| SCHEMBL4702341 | 0.83 | CRHR1 (0.40) | CRHR1 | |
| SCHEMBL4700554 | 0.83 | DRD4 (0.34) | CRHR1 | |
| Trifluoroacetic Acid SCHEMBL4699604 | 0.81 | KDM4E (0.44) | MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1569911-B1 | INDAZOLE DERIVATIVES AS CRF ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2008-07-02 | — | — | EP | claimed |