Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7811994 | 1.00 | POLB (0.42) | POLBALDH1A1LMNAKLF10TSHR | |
| SCHEMBL4703527 | 0.87 | LMNA (0.40) | POLBALDH1A1LMNAKLF10TSHR | |
| SCHEMBL2388710 | 0.85 | TSHR (0.50) | POLBALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL7838761 | 0.80 | MEN1 (0.39) | POLBALDH1A1LMNAKLF10KMT2A | |
| SCHEMBL8388679 | 0.78 | KMT2A (0.37) | POLBALDH1A1LMNAKLF10KMT2A | |
| SCHEMBL4703943 | 0.72 | KMT2A (0.43) | ALDH1A1LMNATSHRKMT2AMEN1 | |
| SCHEMBL9041188 | 0.72 | ALDH1A1 (0.34) | POLBALDH1A1LMNAKLF10KMT2A | |
| SCHEMBL19332726 | 0.71 | CCNC (0.44) | ALDH1A1LMNATSHRL3MBTL1TDP1 | |
| SCHEMBL8963317 | 0.71 | KDM4E (0.40) | POLBALDH1A1KLF10TSHRKMT2A | |
| SCHEMBL7645811 | 0.71 | TOP1 (0.37) | POLBALDH1A1LMNAKLF10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678133-A4 | SEQUENCE SELECTIVE PYRROLE AND IMIDAZOLE POLYAMIDE METALLOCOMPLEXES | UNIV WESTERN SYDNEY (AU) | 2008-06-18 | — | — | EP | disclosed |
| EP-1678133-A1 | SEQUENCE SELECTIVE PYRROLE AND IMIDAZOLE POLYAMIDE METALLOCOMPLEXES | University of Western Sydney (AU) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005033077-A1 | SEQUENCE SELECTIVE PYRROLE AND IMIDAZOLE POLYAMIDE METALLOCOMPLEXES | UNIVERSITY OF WESTERN SYDNEY (AU) | 2005-04-14 | — | — | WO | disclosed |