Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | NPY1R | P25929 | 1/20 | 0.33 |
| ▸ | NPY2R | P49146 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.33 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2388710 | 0.84 | TSHR (0.50) | KDM4ETDP1TSHRGPR35ALDH1A1 | |
| SCHEMBL19332726 | 0.82 | CCNC (0.44) | KDM4ETDP1TSHRGPR35ALDH1A1 | |
| SCHEMBL4703943 | 0.79 | KMT2A (0.43) | KDM4ETDP1TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL7056735 | 0.77 | HPGD (0.45) | KDM4EALDH1A1SMN1; SMN2CYP1A2MEN1 | |
| SCHEMBL7811994 | 0.71 | POLB (0.42) | TDP1TSHRALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL4701010 | 0.71 | POLB (0.42) | TDP1TSHRALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL4703527 | 0.70 | LMNA (0.40) | KDM4ETDP1TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL31124783 | 0.68 | TSHR (0.49) | TDP1TSHRGPR35ALDH1A1SMN1; SMN2 | |
| SCHEMBL20568749 | 0.68 | MAPT (0.40) | KDM4ETDP1TSHRGPR35ALDH1A1 | |
| SCHEMBL8319779 | 0.67 | MAPT (0.46) | KDM4ETDP1TSHRALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696287-A1 | UREIDO DERIVATIVES OF NAPHTHALENEPHOSPHONIC ACIDS AND PROCESS FOR THEIR PREPARATION | PHARMACIA & UPJOHN S.p.A. (IT) | 1996-02-14 | — | — | EP | disclosed |
| WO-1995023806-A2 | UREIDO DERIVATIVES OF NAPHTHALENEPHOSPHONIC ACIDS AND PROCESS FOR THEIR PREPARATION | PHARMACIA S.P.A. (IT) | 1995-09-08 | — | — | WO | disclosed |