Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.54 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.54 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.54 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.54 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.54 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.54 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3470485 | 1.00 | MAOA (0.71) | MAOACYP1A2KMT2ASMN1; SMN2POLB | |
| Acetic Acid SCHEMBL11512680 | 0.93 | CYP1A2 (0.68) | MAOACYP1A2KMT2ASMN1; SMN2POLB | |
| Acetic Acid SCHEMBL11512683 | 0.93 | CYP1A2 (0.68) | MAOACYP1A2KMT2ASMN1; SMN2POLB | |
| SCHEMBL13985373 | 0.88 | FAAH (0.63) | MAOACYP1A2KMT2ASMN1; SMN2POLB | |
| SCHEMBL18251625 | 0.86 | CYP1A2 (0.68) | MAOACYP1A2KMT2ASMN1; SMN2POLB | |
| SCHEMBL20625796 | 0.86 | SCN4A (0.60) | MAOACYP1A2SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL10054978 | 0.86 | KDM4E (0.63) | MAOACYP1A2KMT2ASMN1; SMN2RAB9A | |
| Hydrochloric Acid SCHEMBL18245478 | 0.85 | CYP1A2 (0.66) | MAOACYP1A2KMT2ASMN1; SMN2POLB | |
| Hydrochloric Acid SCHEMBL18245477 | 0.85 | CYP1A2 (0.66) | MAOACYP1A2KMT2ASMN1; SMN2POLB | |
| SCHEMBL7750403 | 0.83 | KMT2A (0.59) | MAOACYP1A2KMT2ASMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001025192-A1 | GUANIDINE DERIVATIVES AND THEIR USE IN THE PRODUCTION OF A MEDICAMENT FOR BLOCKING XANTHINE OXIDASE/DEHYDROGENASE | MELACURE THERAPEUTICS AB (SE) | 2001-04-12 | — | — | WO | claimed |
| EP-3508516-B1 | VULCANIZED RUBBER COMPOSITION AND PRODUCTION PROCESS THEREFOR | MITSUBISHI GAS CHEMICAL CO (JP) | 2020-09-23 | — | — | EP | disclosed |
| EP-3508516-A1 | VULCANIZED RUBBER COMPOSITION AND PRODUCTION PROCESS THEREFOR | Mitsubishi Gas Chemical Company, Inc. (JP) | 2019-07-10 | — | — | EP | disclosed |
| EP-3156394-B1 | ALKYLIDENE AMINOGANIDINE AND SALT THEREOF, MODIFIER COMPOSITION, MODIFIED RUBBER FOR TIRE, RUBBER COMPOSITION FOR TIRE, AND TIRE | MITSUBISHI GAS CHEMICAL CO (JP) | 2019-04-17 | — | — | EP | disclosed |
| US-10246526-B2 | Vulcanized rubber composition and production method thereof | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2019-04-02 | — | — | US | disclosed |
| US-10173973-B2 | Alkylidene aminoguanidine and salt thereof, modifying composition, modified rubber for tire, rubber composition for tire, and tire | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2019-01-08 | — | — | US | disclosed |
| US-20180355074-A1 | VULCANIZED RUBBER COMPOSITION AND PRODUCTION METHOD THEREOF | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2018-12-13 | — | — | US | disclosed |
| US-20170129850-A1 | ALKYLIDENE AMINOGUANIDINE AND SALT THEREOF, MODIFYING COMPOSITION, MODIFIED RUBBER FOR TIRE, RUBBER COMPOSITION FOR TIRE, AND TIRE | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2017-05-11 | — | — | US | disclosed |
| EP-3156394-A1 | ALKYLIDENE AMINOGANIDINE AND SALT THEREOF, MODIFIER COMPOSITION, MODIFIED RUBBER FOR TIRE, RUBBER COMPOSITION FOR TIRE, AND TIRE | Mitsubishi Gas Chemical Company, Inc. (JP) | 2017-04-19 | — | — | EP | disclosed |
| US-20160067257-A1 | SCREENING METHOD AND COMPOUNDS FOR MODULATING TELOMERASE ACTIVITY | THE WISTAR INSTITUTE (US) | 2016-03-10 | — | — | US | disclosed |
| US-9234230-B2 | Screening method and compounds for modulating telomerase activity | THE WISTAR INSTITUTE (US) | 2016-01-12 | — | — | US | disclosed |
| US-8518940-B2 | FP-pocket-binding effectors and methods for using the same to modulate telomerase activity | THE WISTAR INSTITUTE (US) | 2013-08-27 | — | — | US | disclosed |
| US-20120309759-A1 | Screening Method and Compounds for Modulating Telomerase Activity | THE WISTAR INSTITUTE (US) | 2012-12-06 | — | — | US | disclosed |
| WO-2011097600-A1 | SCREENING METHOD AND COMPOUNDS FOR MODULATING TELOMERASE ACTIVITY | THE WISTAR INSTITUTE (US) | 2011-08-11 | — | — | WO | disclosed |
| US-20100158798-A1 | FP-Pocket-Binding Effectors and Methods for Using the Same to Modulate Telomerase Activity | THE WISTAR INSTITUTE | 2010-06-24 | — | — | US | disclosed |
| US-20010044457-A1 | Cancer Treatment | CAMDEN JAMES BERGER (US) | 2001-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170129850-A1 | ALKYLIDENE AMINOGUANIDINE AND SALT THEREOF, MODIFYING COMPOSITION, MODIFIED RUBBER FOR TIRE, RUBBER COMPOSITION FOR TIRE, AND TIRE | TAAR1, PRMT9, RASGRP1 | MAOA 1524/4885CYP1A2 1588/4885KMT2A 1994/4885 |
| US-20120309759-A1 | Screening Method and Compounds for Modulating Telomerase Activity | TERT, TERB1, TERF2 | MAOA 3941/4885CYP1A2 4022/4885KMT2A 2921/4885 |
| US-20100158798-A1 | FP-Pocket-Binding Effectors and Methods for Using the Same to Modulate Telomerase Activity | TERF2IP, TERF2, TERT | MAOA 4242/4885CYP1A2 4657/4885KMT2A 2483/4885 |
| US-20010044457-A1 | Cancer Treatment | EWSR1, ABL1, MUSK | MAOA 2446/4885CYP1A2 707/4885KMT2A 220/4885 |
| US-20160067257-A1 | SCREENING METHOD AND COMPOUNDS FOR MODULATING TELOMERASE ACTIVITY | TERT, TERB1, TERF2 | MAOA 3941/4885CYP1A2 4022/4885KMT2A 2921/4885 |
| US-10173973-B2 | Alkylidene aminoguanidine and salt thereof, modifying composition, modified rubber for tire, rubber composition for tire, and tire | TAAR1, PRMT9, RASGRP1 | MAOA 1524/4885CYP1A2 1588/4885KMT2A 1994/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.