Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 3/20 | 0.40 |
| ▸ | TTK | P33981 | 6/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 9/20 | 0.35 |
| ▸ | CDK2 | P24941 | 9/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 2/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL470186 | 0.79 | TYK2 (0.45) | TYK2TTKCCNE1CDK2FLT3 | |
| SCHEMBL455869 | 0.75 | TYK2 (0.41) | TYK2TTKCCNE1CDK2S1PR1 | |
| SCHEMBL17425401 | 0.73 | TYK2 (0.37) | TYK2TTK | |
| SCHEMBL458280 | 0.72 | TYK2 (0.43) | TYK2TTKCCNE1CDK2FLT3 | |
| SCHEMBL458935 | 0.64 | TTK (0.41) | TTK | |
| SCHEMBL470188 | 0.62 | TTK (0.74) | TTK | |
| SCHEMBL456366 | 0.60 | ERN1 (0.34) | TTK | |
| SCHEMBL470189 | 0.60 | CCNE1 (0.42) | TYK2TTKCCNE1CDK2FLT3 | |
| SCHEMBL456788 | 0.58 | CCNE1 (0.35) | TYK2TTKCCNE1CDK2JAK3 | |
| SCHEMBL456244 | 0.58 | TTK (0.33) | TTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2614063-B1 | SUBSTITUTED IMIDAZOPYRIDAZINES | BAYER IP GMBH (DE) | 2016-01-13 | — | — | EP | disclosed |
| EP-2614063-A1 | SUBSTITUTED IMIDAZOPYRIDAZINES | Bayer Intellectual Property GmbH (DE) | 2013-07-17 | — | — | EP | disclosed |
| WO-2012032031-A1 | SUBSTITUTED IMIDAZOPYRIDAZINES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-03-15 | — | — | WO | disclosed |