Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 8/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4701014 | 0.87 | AR (0.51) | ARATMALDH1A1 | |
| SCHEMBL8393115 | 0.84 | AR (0.48) | ARATMALDH1A1 | |
| SCHEMBL4703944 | 0.75 | HTT (0.40) | ARALDH1A1TP53HTTMAPT | |
| SCHEMBL883063 | 0.71 | MAPK1 (0.43) | ARALDH1A1TP53HTTSMN1; SMN2 | |
| SCHEMBL7838764 | 0.70 | SMN1; SMN2 (0.34) | ATMALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8388682 | 0.68 | MMP14 (0.34) | MAPT | |
| SCHEMBL6800421 | 0.67 | TDP1 (0.44) | ALDH1A1TP53 | |
| SCHEMBL5676062 | 0.65 | AR (0.41) | ARALDH1A1TP53HTTMAPT | |
| SCHEMBL7056737 | 0.65 | ALDH1A1 (0.34) | ARALDH1A1TP53HTTHCAR3 | |
| SCHEMBL5680368 | 0.64 | AR (0.38) | ARALDH1A1TP53HTTKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678133-A4 | SEQUENCE SELECTIVE PYRROLE AND IMIDAZOLE POLYAMIDE METALLOCOMPLEXES | UNIV WESTERN SYDNEY (AU) | 2008-06-18 | — | — | EP | disclosed |
| EP-1678133-A1 | SEQUENCE SELECTIVE PYRROLE AND IMIDAZOLE POLYAMIDE METALLOCOMPLEXES | University of Western Sydney (AU) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005033077-A1 | SEQUENCE SELECTIVE PYRROLE AND IMIDAZOLE POLYAMIDE METALLOCOMPLEXES | UNIVERSITY OF WESTERN SYDNEY (AU) | 2005-04-14 | — | — | WO | disclosed |