SCHEMBL7056737

SCHEMBL7056737

CCn1cc(C[N+](=O)[O-])cc1C(=O)O

nearest known ligand 0.34

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.34
AR P10275 1/20 0.33
HCAR3 P49019 2/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
TP53 P04637 1/20 0.33
HTT P42858 1/20 0.33
GPR35 Q9HC97 1/20 0.33
MCL1 Q07820 1/20 0.32
MAPT P10636 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
CPA1 P15085 3/20 0.30
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7054292 0.81 AR (0.45) ARHCAR3TP53HTTCPA1
SCHEMBL4703944 0.78 HTT (0.40) ALDH1A1ARCA1CA2TP53
SCHEMBL7052816 0.77 MAOA (0.36) ALDH1A1CA12CA1CA2CA9
SCHEMBL2495583 0.71 GPR35 (0.39) ALDH1A1CA12CA1CA2CA9
SCHEMBL874860 0.69 GPR35 (0.38) ALDH1A1CA12CA1CA2CA9
SCHEMBL780340 0.69 GPR35 (0.38) ALDH1A1CA12CA1CA2CA9
SCHEMBL29190982 0.68 GPR35 (0.37) ALDH1A1CA12CA1CA2CA9
SCHEMBL16372656 0.67 GPR35 (0.36) ALDH1A1CA12CA1CA2CA9
SCHEMBL5676062 0.66 AR (0.41) ALDH1A1ARTP53HTTMAPT
SCHEMBL11779027 0.65 CASP6 (0.41) ALDH1A1HCAR3CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003020877-A2 STAINING AND SORTING GENOMES AND CHROMOSOMES USING SEQUENCE-SPECIFIC POLYAMIDES PHARMACIA CORPORATION (US) 2003-03-13 WO disclosed