Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | VNN1 | O95497 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 7/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4706167 | 0.89 | KDM1A (0.51) | HPGDKDM1AMMP8F10 | |
| SCHEMBL4706069 | 0.89 | KDM1A (0.42) | KDM1ACHRM1MMP8F10 | |
| Hydrochloric Acid SCHEMBL4702814 | 0.84 | ALDH1A1 (0.44) | ALDH1A1MAPTHPGDKDM1ACHRM1 | |
| SCHEMBL4705330 | 0.83 | MMP8 (0.43) | ALDH1A1KDM1AMMP8F10 | |
| SCHEMBL4703202 | 0.82 | ALDH1A1 (0.43) | ALDH1A1MAPTF10NAMPT | |
| SCHEMBL4705662 | 0.80 | F10 (0.40) | KDM1AMMP8F10 | |
| SCHEMBL4704210 | 0.79 | F10 (0.68) | F10 | |
| SCHEMBL4705534 | 0.78 | F10 (0.43) | ALDH1A1F10 | |
| SCHEMBL4702122 | 0.78 | F10 (0.41) | F10 | |
| SCHEMBL4702773 | 0.77 | REN (0.40) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567489-B1 | PYRROLIDIN-2-ONE DERIVATIVES AS INHIBITORS OF THROMBIN AND FACTOR XA | GLAXO GROUP LTD (GB) | 2008-07-23 | — | — | EP | disclosed |