Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL28191726 | 0.94 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL28861543 | 0.94 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL17870653 | 0.94 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL6673355 | 0.94 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL10788717 | 0.94 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL5488857 | 0.94 | — | — | |
| Bicarbonate SCHEMBL532723 | 0.94 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL19128 | 0.94 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL711064 | 0.94 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL3266233 | 0.94 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117343795-A | Fish oil and preparation method thereof | 湖北葛店人福药用辅料有限责任公司 | 2024-01-05 | — | — | CN | claimed |
| CN-117125916-A | Long-lasting expansion anti-cracking agent for concrete, preparation method and anti-cracking concrete | 中铁大桥局集团有限公司 | 2023-11-28 | — | — | CN | claimed |
| CN-116376269-A | Antibacterial nylon material and preparation method and application thereof | 江苏金发科技新材料有限公司 | 2023-07-04 | — | — | CN | claimed |
| CN-112708262-B | Polyamide composition and preparation method and application thereof | 江苏金发科技新材料有限公司 | 2022-11-18 | — | — | CN | claimed |
| CN-112358722-B | Polyamide composite material and preparation method and application thereof | 上海金发科技发展有限公司 | 2022-08-09 | — | — | CN | claimed |
| CN-114606056-A | Soybean oil, preparation method thereof and combined adsorbent for preparing soybean oil | 湖北葛店人福药用辅料有限责任公司 | 2022-06-10 | — | — | CN | claimed |
| EP-3612332-B1 | METHOD OF MAKING A MEDICAL DEVICE USING ADDITIVE MANUFACTURING WITH A MASKING PLATE | MEDTRONIC VASCULAR INC (US) | 2022-04-06 | — | — | EP | claimed |
| CN-113943013-A | Method for preparing weather-resistant calcium-aluminum carbonate compound | 太原市小店区巨龙福利加工厂 | 2022-01-18 | — | — | CN | claimed |
| CN-112915960-A | Internal-doped marine reinforced concrete targeted adsorbent and preparation method and application thereof | 中山大学 | 2021-06-08 | — | — | CN | claimed |
| CN-112708262-A | Polyamide composition and preparation method and application thereof | 江苏金发科技新材料有限公司 | 2021-04-27 | — | — | CN | claimed |
| CN-112358722-A | Polyamide composite material and preparation method and application thereof | 上海金发科技发展有限公司 | 2021-02-12 | — | — | CN | claimed |
| CN-108821686-B | Preparation method of aluminum calcium carbonate composite cementing material and product | 浙江大学 | 2020-08-18 | — | — | CN | claimed |
| EP-3612332-A1 | METHOD OF MAKING A MEDICAL DEVICE USING ADDITIVE MANUFACTURING WITH A MASKING PLATE | Medtronic Vascular Inc. (US) | 2020-02-26 | — | — | EP | claimed |
| WO-2018195194-A1 | METHOD OF MAKING A MEDICAL DEVICE USING ADDITIVE MANUFACTURING WITH A MASKING PLATE | MEDTRONIC VASCULAR, INC. (US) | 2018-10-25 | — | — | WO | claimed |
| US-20180303643-A1 | METHOD OF MAKING A MEDICAL DEVICE USING ADDITIVE MANUFACTURING WITH A MASKING PLATE | MEDTRONIC VASCULAR, INC. | 2018-10-25 | — | — | US | claimed |
| US-9283538-B1 | Method of fabricating pelletized medium-high-temperature CO2 sorbent of Ca—Al—CO3 | Institute of Nuclear Energy Research, Atomic Energy Council, Executive Yuan, R.O.C. (TW) | 2016-03-15 | — | — | US | claimed |
| US-20160059207-A1 | Method of Fabricating Pelletized Medium-High-Temperature CO2 Sorbent of Ca-Al-CO3 | Institute of Nuclear Energy Research, Atomic Energy Council, Executive Yuan, R.O.C. (TW) | 2016-03-03 | — | — | US | claimed |
| CN-105056872-A | Novel calcium aluminum carbonate water purification agent preparation method and phosphorus removal process | USTC UNIV SCIENCE TECH CN | 2015-11-18 | — | — | CN | claimed |
| US-9108859-B2 | Engineered process of manufacturing calcium aluminate carbonates for medium-high temperature CO2 capture | INSTITUTE OF NUCLEAR ENERGY RESEARCH, ATOMIC ENERGY COUNCIL (TW) | 2015-08-18 | — | — | US | claimed |
| US-20140072501-A1 | ENGINEERED PROCESS OF MANUFACTURING CALCIUM ALUMINATE CARBONATES FOR MEDIUM-HIGH TEMPERATURE CO2 CAPTURE | ATOMIC ENERGY COUNCIL-INSTITUTE OF NUCLEAR ENERGY RESEARCH (TW) | 2014-03-13 | — | — | US | claimed |