Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CKS1B | P61024 | 1/20 | 0.45 |
| ▸ | SKP1 | P63208 | 1/20 | 0.45 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12064727 | 0.88 | GRIN2B (0.45) | L3MBTL1CKS1BSKP1SKP2MAPT | |
| SCHEMBL470599 | 0.86 | GPR119 (0.43) | CKS1BSKP1SKP2HSD11B1GPR119 | |
| SCHEMBL12064782 | 0.81 | PDE4B (0.42) | L3MBTL1MAPTMAPK1NPSR1MEN1 | |
| SCHEMBL470605 | 0.80 | PDE10A (0.43) | CKS1BSKP1SKP2CTSK | |
| SCHEMBL953899 | 0.80 | HSD11B1 (0.59) | L3MBTL1MEN1KMT2AHSD11B1CTSL | |
| SCHEMBL1971844 | 0.80 | HSD11B1 (0.59) | L3MBTL1MEN1KMT2AHSD11B1CTSL | |
| SCHEMBL1775260 | 0.80 | HSD11B1 (0.59) | L3MBTL1MEN1KMT2AHSD11B1CTSL | |
| SCHEMBL951538 | 0.79 | KMT2A (0.59) | L3MBTL1MAPTMAPK1NPSR1MEN1 | |
| SCHEMBL4324325 | 0.78 | SMN1; SMN2 (0.56) | L3MBTL1MEN1KMT2AHSD11B1CTSL | |
| SCHEMBL17140621 | 0.78 | SMN1; SMN2 (0.56) | L3MBTL1MEN1KMT2AHSD11B1CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |