Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 3/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.33 |
| ▸ | F9 | P00740 | 2/20 | 0.33 |
| ▸ | PLAU | P00749 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | NPR1 | P16066 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14343632 | 0.94 | CTSK (0.35) | KDM4EALDH1A1TDP1F10TAS1R3 | |
| SCHEMBL4708769 | 0.85 | KDM4C (0.40) | KDM4EOPRM1KMT2ANPY5R | |
| SCHEMBL4708832 | 0.85 | KDM4C (0.38) | KDM4EOPRM1KMT2ANPY5R | |
| SCHEMBL4707353 | 0.83 | CNR1 (0.36) | KDM4EALDH1A1OPRM1KMT2ANPY5R | |
| SCHEMBL4190982 | 0.83 | HTR1A (0.36) | KDM4EALDH1A1TDP1TAS1R3TAS1R1 | |
| SCHEMBL4707716 | 0.82 | GCK (0.35) | KDM4EALDH1A1OPRM1KMT2ANPY5R | |
| SCHEMBL4187987 | 0.82 | OPRM1 (0.46) | F10TAS1R3TAS1R1OPRM1NPY5R | |
| SCHEMBL14343589 | 0.81 | CNR1 (0.38) | — | |
| SCHEMBL4706438 | 0.80 | F10 (0.40) | F10TAS1R3TAS1R1F9PLAU | |
| SCHEMBL4200116 | 0.79 | HCAR1 (0.38) | KDM4EALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879877-B1 | ANTIMICROBIAL AGENTS | RANBAXY LAB LTD (IN) | 2013-01-02 | — | — | EP | disclosed |
| EP-1879877-A2 | ANTIMICROBIAL AGENTS | Ranbaxy Laboratories Limited (IN) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006117762-A2 | ANTIMICROBIAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-11-09 | — | — | WO | disclosed |