Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 3/20 | 0.33 |
| ▸ | TACR1 | P25103 | 2/20 | 0.31 |
| ▸ | RORB | Q92753 | 1/20 | 0.30 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4706116 | 0.96 | RORC (0.35) | RORCTACR1RORBKDM4C | |
| SCHEMBL4639531 | 0.94 | RORC (0.34) | RORCTACR1RORB | |
| SCHEMBL4637800 | 0.90 | RORC (0.36) | RORCTACR1RORB | |
| SCHEMBL4638885 | 0.88 | TRPV1 (0.32) | RORCTACR1KDM4C | |
| SCHEMBL4706769 | 0.86 | RORC (0.33) | RORCTACR1RORBKDM4C | |
| SCHEMBL4639414 | 0.85 | MAPK1 (0.36) | RORCTACR1RORB | |
| SCHEMBL4638833 | 0.83 | RORB (0.35) | RORCTACR1RORB | |
| SCHEMBL4638809 | 0.83 | ALDH1A1 (0.36) | RORCKDM4C | |
| SCHEMBL4638821 | 0.82 | TACR1 (0.32) | RORCTACR1 | |
| SCHEMBL4638022 | 0.82 | RORB (0.33) | RORCTACR1RORB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501809-B1 | TRIAZOLE DERIVATIVES AS TACHYKININ RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 2008-01-16 | — | — | EP | disclosed |