Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.37 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.37 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.37 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.37 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.37 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL458609 | 0.93 | KMT2A (0.50) | KMT2AMAPTLMNASMN1; SMN2KDM4E | |
| SCHEMBL457816 | 0.85 | LMNA (0.40) | KMT2AMAPTLMNASMN1; SMN2KDM4E | |
| SCHEMBL458557 | 0.84 | ALDH1A1 (0.41) | KMT2AMAPTLMNASMN1; SMN2KDM4E | |
| SCHEMBL458358 | 0.82 | MAPT (0.43) | KMT2AMAPTLMNATUBB4ATUBB | |
| SCHEMBL458031 | 0.78 | KMT2A (0.48) | KMT2AMAPTLMNASMN1; SMN2KDM4E | |
| SCHEMBL470704 | 0.76 | PTGS2 (0.36) | KMT2ALMNASMN1; SMN2POLBMEN1 | |
| SCHEMBL26087274 | 0.76 | KMT2A (0.51) | KMT2AMAPTKDM4EPOLBMEN1 | |
| SCHEMBL6130221 | 0.76 | KMT2A (0.62) | KMT2AMAPTLMNAMEN1ALDH1A1 | |
| SCHEMBL23494962 | 0.76 | KMT2A (0.47) | KMT2AMAPTSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL458326 | 0.75 | CYP1A2 (0.39) | LMNAKDM4EHTR6ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012031358-A1 | BIARYL DIPHOSPHINE LIGANDS, INTERMEDIATES OF THE SAME AND THEIR USE IN ASYMMETRIC CATALYSIS | KANATA CHEMICAL TECHNOLOGIES INC. (CA) | 2012-03-15 | — | — | WO | disclosed |