Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL470696 | 0.93 | KMT2A (0.45) | KMT2AMAPTLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL458358 | 0.89 | MAPT (0.43) | KMT2AMAPTLMNAALDH1A1CYP3A4 | |
| SCHEMBL457816 | 0.86 | LMNA (0.40) | KMT2AMAPTLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL458031 | 0.84 | KMT2A (0.48) | KMT2AMAPTLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL6130221 | 0.82 | KMT2A (0.62) | KMT2AMAPTLMNAALDH1A1MEN1 | |
| SCHEMBL23494962 | 0.81 | KMT2A (0.47) | KMT2AMAPTSMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL458557 | 0.81 | ALDH1A1 (0.41) | KMT2AMAPTLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL14754995 | 0.79 | KMT2A (0.62) | KMT2AMAPTLMNAALDH1A1MEN1 | |
| SCHEMBL470702 | 0.79 | PTGS2 (0.38) | KMT2AMAPTLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL458326 | 0.78 | CYP1A2 (0.39) | LMNAALDH1A1CYP3A4CYP1A2HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9062085-B2 | Biaryl diphosphine ligands, intermediates of the same and their use in asymmetric catalysis | KANATA CHEMICAL TECHNOLOGIES INC. (CA) | 2015-06-23 | — | — | US | disclosed |
| US-9062085-B2 | Biaryl diphosphine ligands, intermediates of the same and their use in asymmetric catalysis | KANATA CHEMICAL TECHNOLOGIES INC. (CA) | 2015-06-23 | — | — | US | disclosed |
| US-9062085-B2 | Biaryl diphosphine ligands, intermediates of the same and their use in asymmetric catalysis | KANATA CHEMICAL TECHNOLOGIES INC. (CA) | 2015-06-23 | — | — | US | disclosed |
| US-20130184479-A1 | BIARYL DIPHOSPHINE LIGANDS, INTERMEDIATES OF THE SAME AND THEIR USE IN ASYMMETRIC CATALYSIS | KANATA CHEMICAL TECHNOLOGIES INC. (CA) | 2013-07-18 | — | — | US | disclosed |
| US-20130184479-A1 | BIARYL DIPHOSPHINE LIGANDS, INTERMEDIATES OF THE SAME AND THEIR USE IN ASYMMETRIC CATALYSIS | KANATA CHEMICAL TECHNOLOGIES INC. (CA) | 2013-07-18 | — | — | US | disclosed |
| US-20130184479-A1 | BIARYL DIPHOSPHINE LIGANDS, INTERMEDIATES OF THE SAME AND THEIR USE IN ASYMMETRIC CATALYSIS | KANATA CHEMICAL TECHNOLOGIES INC. (CA) | 2013-07-18 | — | — | US | disclosed |
| EP-2614069-A1 | BIARYL DIPHOSPHINE LIGANDS, INTERMEDIATES OF THE SAME AND THEIR USE IN ASYMMETRIC CATALYSIS | Kanata Chemical Technologies Inc. (CA) | 2013-07-17 | — | — | EP | disclosed |
| WO-2012031358-A1 | BIARYL DIPHOSPHINE LIGANDS, INTERMEDIATES OF THE SAME AND THEIR USE IN ASYMMETRIC CATALYSIS | KANATA CHEMICAL TECHNOLOGIES INC. (CA) | 2012-03-15 | — | — | WO | disclosed |
| WO-2012031358-A1 | BIARYL DIPHOSPHINE LIGANDS, INTERMEDIATES OF THE SAME AND THEIR USE IN ASYMMETRIC CATALYSIS | KANATA CHEMICAL TECHNOLOGIES INC. (CA) | 2012-03-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130184479-A1 | BIARYL DIPHOSPHINE LIGANDS, INTERMEDIATES OF THE SAME AND THEIR USE IN ASYMMETRIC CATALYSIS | AGPS, COASY, BLVRB | KMT2A 2699/4885MAPT 4543/4885LMNA 4638/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.