Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | GHSR | Q92847 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 3/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.34 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HPGDS | O60760 | 2/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4709029 | 0.85 | KDM4E (0.49) | KDM4EPKMLMNAPOLBALDH1A1 | |
| SCHEMBL4709795 | 0.83 | KDM4E (0.49) | KDM4EPKMLMNAPOLBALDH1A1 | |
| SCHEMBL4199632 | 0.83 | GHSR (0.43) | KDM4EPKMGHSRLMNAPOLB | |
| SCHEMBL4706576 | 0.83 | KDM4E (0.44) | KDM4EPKMGHSRLMNAPOLB | |
| SCHEMBL4189904 | 0.83 | GHSR (0.43) | KDM4EPKMGHSRLMNAPOLB | |
| SCHEMBL4706121 | 0.83 | KDM4E (0.44) | KDM4EPKMLMNAPOLBALDH1A1 | |
| SCHEMBL4198243 | 0.82 | GHSR (0.43) | KDM4EPKMGHSRLMNAPOLB | |
| SCHEMBL4707002 | 0.81 | KDM4E (0.48) | KDM4EPKMLMNAPOLBALDH1A1 | |
| SCHEMBL4706976 | 0.80 | PKM (0.46) | KDM4EPKMLMNAPOLBALDH1A1 | |
| SCHEMBL4708104 | 0.78 | PKM (0.56) | KDM4EPKMLMNAPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879877-A2 | ANTIMICROBIAL AGENTS | Ranbaxy Laboratories Limited (IN) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006117762-A2 | ANTIMICROBIAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-11-09 | — | — | WO | disclosed |