Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | GHSR | Q92847 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CKS1B | P61024 | 1/20 | 0.33 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | CDK1 | P06493 | 3/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.32 |
| ▸ | CDK2 | P24941 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4706121 | 0.86 | KDM4E (0.44) | KDM4EPKMLMNAPOLBALDH1A1 | |
| SCHEMBL4709795 | 0.83 | KDM4E (0.49) | KDM4EPKMLMNAPOLBALDH1A1 | |
| SCHEMBL4709029 | 0.83 | KDM4E (0.49) | KDM4EPKMLMNAPOLBALDH1A1 | |
| SCHEMBL4200217 | 0.83 | GHSR (0.43) | KDM4EPKMGHSRLMNAPOLB | |
| SCHEMBL4194983 | 0.83 | GHSR (0.43) | KDM4EPKMGHSRLMNAPOLB | |
| SCHEMBL4707040 | 0.83 | KDM4E (0.44) | KDM4EPKMGHSRLMNAPOLB | |
| SCHEMBL4195580 | 0.82 | GHSR (0.43) | KDM4EPKMGHSRLMNAPOLB | |
| SCHEMBL4707002 | 0.81 | KDM4E (0.48) | KDM4EPKMLMNAPOLBALDH1A1 | |
| SCHEMBL4706976 | 0.80 | PKM (0.46) | KDM4EPKMLMNAPOLBALDH1A1 | |
| SCHEMBL4708673 | 0.79 | ALDH1A1 (0.44) | KDM4EPKMLMNAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879877-A2 | ANTIMICROBIAL AGENTS | Ranbaxy Laboratories Limited (IN) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006117762-A2 | ANTIMICROBIAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-11-09 | — | — | WO | disclosed |