SCHEMBL4707286

SCHEMBL4707286

Cc1cc(C)c([SiH](O[PH](=O)O[SiH](c2c(C)cc(C)cc2C)c2c(C)cc(C)cc2C)c2c(C)cc(C)cc2C)c(C)c1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7195553 0.83 TPMT (0.31)
SCHEMBL3296111 0.74 RAPGEF4 (0.38) RAPGEF4
SCHEMBL4707744 0.67 ALDH1A1 (0.39)
SCHEMBL10979164 0.65 GRIN2D (0.35) RAPGEF4
SCHEMBL8384863 0.65 RAPGEF4 (0.50) RAPGEF4
SCHEMBL1726231 0.65 RAPGEF4 (0.43) RAPGEF4
SCHEMBL23414342 0.63 KMT2A (0.33)
SCHEMBL8380464 0.63 RAPGEF4 (0.41) RAPGEF4
SCHEMBL29776866 0.63 RAPGEF4 (0.41) RAPGEF4
SCHEMBL1635401 0.63 RAPGEF4 (0.41) RAPGEF4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1368384-B1 MANUFACTURE OF CONJUGATED DIENE POLYMERS USING AN IRON-BASED CATALYST COMPOSITION BRIDGESTONE CORP (JP) 2008-08-20 EP disclosed
EP-1368384-A1 MANUFACTURE OF CONJUGATED DIENE POLYMERS USING AN IRON-BASED CATALYST COMPOSITION Bridgestone Corporation (JP) 2003-12-10 EP disclosed
US-6627712-B2 Reaction product of an iron-containing compound, a silyl phosphonate, and an organoaluminum compound to polymerize 1,3-butadiene into syndiotactic 1,2-polybutadiene BRIDGESTONE CORPORATION (JP) 2003-09-30 US disclosed
WO-2002100910-A1 MOLYBDENUM-BASED CATALYST COMPOSITION FOR PRODUCING SYNDIOTACTIC 1,2-POLYBUTADIENE BRIDGESTONE CORPORATION (JP) 2002-12-19 WO disclosed
US-20020156210-A1 Manufacture of conjugated diene polymers by using an iron-based catalyst composition BRIDGESTONE CORP. 2002-10-24 US disclosed
WO-2002081082-A1 IRON-BASED CATALYST COMPOSITION FOR PRODUCING OLIGOMERS OF CONJUGATED DIENES BRIDGESTONE CORPORATION (JP) 2002-10-17 WO disclosed
WO-2002066525-A1 CHROMIUM-BASED CATALYST COMPOSITION BRIDGESTONE CORPORATION (JP) 2002-08-29 WO disclosed
WO-2002066523-A1 MANUFACTURE OF CONJUGATED DIENE POLYMERS USING AN IRON-BASED CATALYST COMPOSITION BRIDGESTONE CORPORATION (JP) 2002-08-29 WO disclosed
US-20020115558-A1 CHROMIUM-BASED CATALYST COMPOSITION FOR PRODUCING CONJUGATED DIENE POLYMERS BRIDGESTONE CORP. 2002-08-22 US disclosed
US-6433237-B1 USING COORDINATION CATALYST BRIDGESTONE CORPORATION (JP) 2002-08-13 US disclosed