SCHEMBL1635401

SCHEMBL1635401

Cc1cc(C)c([SiH](C)C)c(C)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 8/20 0.41
ALDH1A1 P00352 4/20 0.35
KDM4E B2RXH2 2/20 0.35
LMNA P02545 1/20 0.35
GAA P10253 1/20 0.35
MAPT P10636 1/20 0.35
TSHR P16473 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2A6 P11509 1/20 0.33
TP53 P04637 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
MMP1 P03956 1/20 0.31
MMP2 P08253 1/20 0.31
MMP9 P14780 1/20 0.31
MMP8 P22894 1/20 0.31
MMP13 P45452 1/20 0.31
GRIN2D O15399 1/20 0.31
GRIN3B O60391 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29776866 0.81 RAPGEF4 (0.41) RAPGEF4ALDH1A1KDM4ELMNAGAA
SCHEMBL8384863 0.78 RAPGEF4 (0.50) RAPGEF4ALDH1A1KDM4ELMNAGAA
SCHEMBL1726231 0.78 RAPGEF4 (0.43) RAPGEF4ALDH1A1KDM4ELMNAGAA
SCHEMBL8380464 0.75 RAPGEF4 (0.41) RAPGEF4ALDH1A1KDM4ELMNAGAA
SCHEMBL23414017 0.73 RAPGEF4 (0.39) RAPGEF4ALDH1A1KDM4ELMNAGAA
SCHEMBL3482381 0.73 RAPGEF4 (0.39) RAPGEF4ALDH1A1KDM4ELMNAGAA
SCHEMBL26265074 0.73 RAPGEF4 (0.39) RAPGEF4ALDH1A1KDM4ELMNAGAA
SCHEMBL3482176 0.73 RAPGEF4 (0.39) RAPGEF4ALDH1A1KDM4ELMNAGAA
SCHEMBL8382049 0.73 RAPGEF4 (0.39) RAPGEF4ALDH1A1KDM4ELMNAGAA
SCHEMBL8386089 0.71 RAPGEF4 (0.33) RAPGEF4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3093303-B1 PHOTOCURABLE COMPOSITION AND CURED PRODUCT SHINETSU CHEMICAL CO (JP) 2019-08-28 EP disclosed
US-20160333171-A1 PHOTOCURABLE COMPOSITION AND CURED PRODUCT SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-11-17 US disclosed
EP-3093303-A1 PHOTOCURABLE COMPOSITION AND CURED PRODUCT Shin-Etsu Chemical Co., Ltd. (JP) 2016-11-16 EP disclosed
US-7932592-B2 Exhibits a light emission color with significantly high purity , highly efficient, highly luminant, and long-lived light emission; high glass transition temperature, heat stability and superior durability CANON KABUSHIKI KAISHA (JP) 2011-04-26 US disclosed
US-7740958-B2 organic compound-containing layers sandwiched between the pair of electrodes; compound has anthracene group is directly bonded to a silyl group and an amino group, and a fluorene compound; energy transfer allows the emission with high color purity; long-life optical output; efficiency at low voltage CANON KABUSHIKI KAISHA (JP) 2010-06-22 US disclosed
US-20080124577-A1 Exhibits a light emission color with significantly high purity , highly efficient, highly luminant, and long-lived light emission; high glass transition temperature, heat stability and superior durability CANON KABUSHIKI KAISHA (JP) 2008-05-29 US disclosed
US-7365198-B2 Silyl compound, light emitting material, and organic light emitting device using the same CANON KABUSHIKI KAISHA (JP) 2008-04-29 US disclosed
US-20070207346-A1 ORGANIC LIGHT-EMITTING DEVICE CANON KABUSHIKI KAISHA (JP) 2007-09-06 US disclosed
US-20070205715-A1 SILYL COMPOUND, LIGHT EMITTING MATERIAL, AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME CANON KABUSHIKI KAISHA (JP) 2007-09-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070205715-A1 SILYL COMPOUND, LIGHT EMITTING MATERIAL, AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME LAS1L, CCNL2, EML4 RAPGEF4 4457/4885ALDH1A1 305/4885KDM4E 1577/4885
US-20080124577-A1 Exhibits a light emission color with significantly high purity , highly efficient, highly luminant, and long-lived light emission; high glass transition temperature, heat stability and superior durability LEF1, MAP1LC3A, HSF1 RAPGEF4 863/4885ALDH1A1 726/4885KDM4E 2484/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.