SCHEMBL4707384

SCHEMBL4707384

CC(CNCc1ncccc1NS(=O)(=O)c1cccs1)C1CCCCC1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFKBIA P25963 1/20 0.46
RELA Q04206 1/20 0.46
GLO1 Q04760 1/20 0.46
TSHR P16473 2/20 0.45
TP53 P04637 2/20 0.45
LMNA P02545 1/20 0.45
ALOX15 P16050 1/20 0.45
OPRK1 P41145 1/20 0.45
HTT P42858 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
TLR9 Q9NR96 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
NPC1 O15118 2/20 0.43
ALDH1A1 P00352 7/20 0.43
MMP2 P08253 2/20 0.41
PKM P14618 1/20 0.41
MCOLN3 Q8TDD5 1/20 0.41
MAPT P10636 3/20 0.40
POLB P06746 1/20 0.40
MAPK1 P28482 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4708604 0.82 ALDH1A1 (0.42) NFKBIARELAGLO1TSHRTP53
SCHEMBL4192695 0.81 NFKBIA (0.46) NFKBIARELAGLO1TSHRTP53
SCHEMBL4708756 0.79 KDM4E (0.41) TSHRLMNANPSR1TDP1NPC1
SCHEMBL4707118 0.76 KDM4E (0.40) TSHRNPSR1ALDH1A1KDM4EGAA
SCHEMBL4707534 0.76 PKM (0.44) LMNANPC1ALDH1A1PKMMCOLN3
SCHEMBL4708553 0.75 ALDH1A1 (0.48) LMNAHTTNPC1ALDH1A1PKM
SCHEMBL4706182 0.75 NPC1 (0.47) TP53HTTNPC1ALDH1A1PKM
SCHEMBL4707576 0.75 NPC1 (0.45) LMNAHTTNPC1ALDH1A1PKM
SCHEMBL4707205 0.74 ALDH1A1 (0.49) LMNAHTTNPC1ALDH1A1PKM
SCHEMBL4707955 0.73 PKM (0.53) LMNAHTTNPSR1NPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1879877-A2 ANTIMICROBIAL AGENTS Ranbaxy Laboratories Limited (IN) 2008-01-23 EP disclosed
WO-2006117762-A2 ANTIMICROBIAL AGENTS RANBAXY LABORATORIES LIMITED (IN) 2006-11-09 WO disclosed