Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 7/20 | 0.39 |
| ▸ | POLB | P06746 | 6/20 | 0.39 |
| ▸ | TP53 | P04637 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | DDX3X | O00571 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4707534 | 0.84 | PKM (0.44) | PKMKDM4EALDH1A1LMNAPOLB | |
| SCHEMBL4708104 | 0.82 | PKM (0.56) | PKMKDM4EALDH1A1LMNAPOLB | |
| SCHEMBL4709029 | 0.82 | KDM4E (0.49) | PKMKDM4EALDH1A1LMNAPOLB | |
| SCHEMBL4707002 | 0.82 | KDM4E (0.48) | PKMKDM4EALDH1A1LMNAPOLB | |
| SCHEMBL4193445 | 0.81 | KDM4E (0.46) | PKMKDM4EALDH1A1LMNAPOLB | |
| SCHEMBL4709526 | 0.81 | KDM4E (0.54) | PKMKDM4EALDH1A1LMNAPOLB | |
| SCHEMBL4706347 | 0.81 | KDM4E (0.50) | PKMKDM4EALDH1A1LMNAPOLB | |
| SCHEMBL4707448 | 0.80 | KDM4E (0.47) | PKMKDM4EALDH1A1LMNAPOLB | |
| SCHEMBL4708790 | 0.79 | PKM (0.46) | PKMKDM4EALDH1A1LMNAPOLB | |
| SCHEMBL4708306 | 0.79 | PKM (0.46) | PKMKDM4EALDH1A1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879877-A2 | ANTIMICROBIAL AGENTS | Ranbaxy Laboratories Limited (IN) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006117762-A2 | ANTIMICROBIAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-11-09 | — | — | WO | disclosed |