Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.30 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12064611 | 0.91 | DPP4 (0.34) | DPP4KCNH2GPR119 | |
| SCHEMBL462652 | 0.76 | NPC1 (0.31) | — | |
| SCHEMBL470662 | 0.75 | GPR119 (0.33) | DPP4KCNH2GPR119 | |
| SCHEMBL470626 | 0.74 | GPR119 (0.49) | DPP4KCNH2GPR119 | |
| SCHEMBL12064798 | 0.73 | GPR119 (0.40) | DPP4KCNH2GPR119 | |
| SCHEMBL12064555 | 0.72 | GPR119 (0.35) | DPP4KCNH2GPR119 | |
| SCHEMBL470918 | 0.71 | GPR119 (0.33) | DPP4KCNH2GPR119 | |
| SCHEMBL122282 | 0.71 | DPP4 (0.39) | DPP4KCNH2 | |
| SCHEMBL470624 | 0.71 | GPR119 (0.33) | DPP4KCNH2GPR119 | |
| SCHEMBL145106 | 0.71 | DPP4 (0.32) | DPP4KCNH2GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |