Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4790285 | 0.86 | NFE2L2 (0.48) | KDM4ETDP1CYP3A4ALOX12KMT2A | |
| SCHEMBL4790286 | 0.86 | NFE2L2 (0.48) | KDM4ETDP1CYP3A4ALOX12KMT2A | |
| SCHEMBL4714220 | 0.81 | KDM4E (0.45) | KDM4ETDP1CYP3A4ALOX12KMT2A | |
| SCHEMBL4714219 | 0.81 | KDM4E (0.45) | KDM4ETDP1CYP3A4ALOX12KMT2A | |
| SCHEMBL3097025 | 0.69 | MEN1 (0.54) | KDM4ETDP1CYP3A4KMT2AMEN1 | |
| SCHEMBL3097012 | 0.69 | MEN1 (0.54) | KDM4ETDP1CYP3A4KMT2AMEN1 | |
| SCHEMBL13647052 | 0.69 | MEN1 (0.54) | KDM4ETDP1CYP3A4KMT2AMEN1 | |
| SCHEMBL1622556 | 0.69 | KDM4E (0.58) | KDM4ETDP1CYP3A4ALOX12KMT2A | |
| SCHEMBL3737609 | 0.69 | ABCB11 (0.49) | KDM4ETDP1CYP3A4ALOX12KMT2A | |
| SCHEMBL28188355 | 0.69 | ABCB11 (0.49) | KDM4ETDP1CYP3A4ALOX12KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0998459-B1 | PYRIDINE DERIVATIVES | NOVARTIS AG (CH) | 2008-04-23 | — | — | EP | claimed |