SCHEMBL3737609

SCHEMBL3737609

CC(=O)Oc1cc(Cl)ccc1Cl

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCB11 O95342 1/20 0.49
KDM4E B2RXH2 5/20 0.45
TDP1 Q9NUW8 2/20 0.45
CYP3A4 P08684 1/20 0.45
ALOX12 P18054 1/20 0.45
NR1H4 Q96RI1 1/20 0.45
ALDH1A1 P00352 3/20 0.44
TP53 P04637 2/20 0.44
F2 P00734 1/20 0.44
GAA P10253 2/20 0.43
RAB9A P51151 2/20 0.43
TSHR P16473 1/20 0.43
GLA P06280 1/20 0.43
GFER P55789 1/20 0.43
HTT P42858 1/20 0.43
KMT2A Q03164 3/20 0.42
MEN1 O00255 2/20 0.42
CYP4F2 P78329 1/20 0.42
CYP4A11 Q02928 1/20 0.42
MRGPRX4 Q96LA9 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28188355 1.00 ABCB11 (0.49) ABCB11KDM4ETDP1CYP3A4ALOX12
SCHEMBL11338058 0.86 KDM4E (0.58) ABCB11KDM4ETDP1NR1H4ALDH1A1
SCHEMBL134715 0.84 KMT2A (0.57) ABCB11KDM4ETDP1NR1H4ALDH1A1
SCHEMBL6869400 0.82 ACHE (0.59) ABCB11KDM4ETDP1NR1H4ALDH1A1
SCHEMBL21328028 0.82 KMT2A (0.55) ABCB11KDM4ETDP1NR1H4ALDH1A1
SCHEMBL21328040 0.82 KMT2A (0.55) ABCB11KDM4ETDP1NR1H4ALDH1A1
SCHEMBL21328030 0.82 KMT2A (0.55) ABCB11KDM4ETDP1NR1H4ALDH1A1
SCHEMBL21328026 0.82 KMT2A (0.55) ABCB11KDM4ETDP1NR1H4ALDH1A1
SCHEMBL28782069 0.82 KMT2A (0.55) ABCB11KDM4ETDP1NR1H4ALDH1A1
SCHEMBL17294832 0.82 CYP4F2 (0.62) ABCB11KDM4ETDP1NR1H4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-59065038-A None JP disclosed
CN-120121751-A Method for detecting chlorophenols in waste gas and application thereof 华电莱州发电有限公司 2025-06-10 CN disclosed
CN-114163325-B Method for synthesizing dicamba by using continuous flow reactor 江苏优嘉植物保护有限公司 2024-06-28 CN disclosed
CN-115054600-B Aromatic sulfonamide derivatives 拜耳制药股份公司 2024-06-14 CN disclosed
CN-111822032-B Catalyst for synthesizing 2,5-dichlorophenol and in-situ synthesis method of 2,5-dichlorophenol 江苏扬农化工集团有限公司 2023-01-24 CN disclosed
CN-115054600-A Aromatic sulfonamide derivatives 拜耳制药股份公司 2022-09-16 CN disclosed
CN-114984003-A Aromatic sulfonamide derivatives 拜耳制药股份公司 2022-09-02 CN disclosed
CN-109415321-B Aromatic sulfonamide derivatives 拜耳制药股份公司 2022-06-17 CN disclosed
US-11274076-B2 Process for preparing 1, 2-benzenedimethanol compound GOWAN COMPANY, L.L.C. (US) 2022-03-15 US disclosed
CN-114163325-A Method for synthesizing dicamba by using continuous flow reactor 江苏优嘉植物保护有限公司 2022-03-11 CN disclosed
US-20080262070-A1 Pharmaceutically Active Tetrahydro-Pyrrolizinone Compounds BAUMANN KARL 2008-10-23 US disclosed
EP-1937685-A1 TETRAHYDRO-PYRROLIZINONE COMPOUNDS AS LFA-I MEDIATORS Novartis AG (CH) 2008-07-02 EP disclosed
EP-1935916-A1 POLYARYLENE AND PROCESS FOR PRODUCING THE SAME Sumitomo Chemical Company, Limited (JP) 2008-06-25 EP disclosed
EP-1857482-A1 POLYARYLENE BLOCK COPOLYMER AND USE THEREOF Sumitomo Chemical Company, Limited (JP) 2007-11-21 EP disclosed
WO-2007039286-A1 TETRAHYDRO-PYRROLIZINONE COMPOUNDS AS LFA-I MEDIATORS NOVARTIS AG (CH) 2007-04-12 WO disclosed
EP-0466569-B1 Process for preparation of N-phenylacetyl derivative of tetrahydrothieno[3,2-c]pyridine and intermediate of synthesis SANOFI SA (FR) 1996-04-17 EP disclosed
EP-0466569-A1 Process for preparation of N-phenylacetyl derivative of tetrahydrothieno[3,2-c]pyridine and intermediate of synthesis SANOFI (FR) 1992-01-15 EP disclosed
JP-S5965038-A SYNTHESIS OF 3,6-DICHLORO-2-HYDROXYACETOPHENONE SHIONOGI & CO LTD 1984-04-13 JP disclosed
US-4326882-A Trichlorophenoxy alkanoic acid free of chlorinated dibenzo-p-dioxins PPG INDUSTRIES, INC. (US) 1982-04-27 US disclosed
US-4293707-A Process for preparing trichlorophenoxy alkanoic acid and hydrolyzable derivatives thereof free of chlorinated dibenzo-p-dioxins PPG INDUSTRIES, INC. (US) 1981-10-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080262070-A1 Pharmaceutically Active Tetrahydro-Pyrrolizinone Compounds VCAM1, ICAM1, EPCAM ABCB11 1805/4885KDM4E 3500/4885TDP1 1760/4885
US-11274076-B2 Process for preparing 1, 2-benzenedimethanol compound ADH1A, ADH1C, CYP2E1 ABCB11 281/4885KDM4E 3316/4885TDP1 3387/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.