Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HPGDS | O60760 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.37 |
| ▸ | PLK1 | P53350 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.35 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.35 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.35 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27772795 | 0.83 | POLB (0.39) | HPGDPOLBSMN1; SMN2KDM4EKMT2A | |
| SCHEMBL27729808 | 0.80 | POLB (0.39) | POLBKDM4EKMT2AHSD17B10MAPT | |
| SCHEMBL28269734 | 0.77 | HPGD (0.42) | ALDH1A1HPGDHPGDSLMNANUDT1 | |
| SCHEMBL18860720 | 0.77 | ALDH1A1 (0.44) | ALDH1A1HPGDHPGDSLMNANUDT1 | |
| SCHEMBL4781208 | 0.75 | PLK1 (0.41) | ALDH1A1HPGDSLMNAPLK1POLB | |
| SCHEMBL27592899 | 0.70 | ACHE (0.41) | ALDH1A1HPGDKDM4EKMT2AMAPT | |
| SCHEMBL365712 | 0.70 | PLK1 (0.45) | ALDH1A1HPGDHPGDSLMNANUDT1 | |
| SCHEMBL9688407 | 0.69 | ACHE (0.39) | ALDH1A1LMNASMN1; SMN2KDM4EKMT2A | |
| SCHEMBL13687250 | 0.69 | BAZ2B (0.37) | ALDH1A1HPGDPLK1SMN1; SMN2KDM4E | |
| SCHEMBL20869079 | 0.69 | PDE3B (0.44) | ALDH1A1HPGDHPGDSNUDT1PLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1909788-A2 | PHARMACEUTICAL COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF COMPLEX DISEASES AND THEIR DELIVERY BY INSERTABLE MEDICAL DEVICES | RESVERLOGIX CORP. (CA) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007016525-A2 | PHARMACEUTICAL COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF COMPLEX DISEASES AND THEIR DELIVERY BY INSERTABLE MEDICAL DEVICES | RESVERLOGIX CORP. (CA) | 2007-02-08 | — | — | WO | disclosed |