Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 2/20 | 0.45 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.39 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.39 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.39 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
| ▸ | ULK1 | O75385 | 1/20 | 0.38 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.38 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.38 |
| ▸ | ULK2 | Q8IYT8 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1515815 | 0.76 | POLB (0.49) | PLK1ALDH1A1POLBLMNA | |
| SCHEMBL1534502 | 0.74 | RAB9A (0.61) | PLK1ALDH1A1HPGDPOLBLMNA | |
| SCHEMBL18860720 | 0.72 | ALDH1A1 (0.44) | PLK1NUDT1ALDH1A1HPGDPDE4D | |
| SCHEMBL21689951 | 0.72 | ALDH1A1 (0.51) | PLK1ALDH1A1HPGDPOLBPDE3B | |
| SCHEMBL4396043 | 0.72 | ACHE (0.48) | ALDH1A1HPGD | |
| SCHEMBL9370908 | 0.71 | ALDH1A1 (0.54) | PLK1ALDH1A1HPGDPOLBPDE3B | |
| SCHEMBL6392944 | 0.71 | PLK1 (0.60) | PLK1ALDH1A1HPGDPDE4D | |
| SCHEMBL6270454 | 0.71 | FAAH (0.59) | ALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL19880900 | 0.71 | KDM4E (0.39) | PLK1ALDH1A1HPGDPDE4DHPGDS | |
| Hydrochloric Acid SCHEMBL27655722 | 0.70 | PLK1 (0.58) | PLK1ALDH1A1HPGDPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F.HOFFMANN-LA ROCHE AG (CH) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007365-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-01-19 | — | — | WO | disclosed |