Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1D1 | P20393 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4022922 | 0.88 | EPHX1 (0.39) | EPHX1MAPTTRPV1LMNAALDH1A1 | |
| SCHEMBL4711910 | 0.85 | MAPT (0.40) | EPHX1MAPTPOLBTRPV1LMNA | |
| SCHEMBL4711906 | 0.85 | EPHX1 (0.38) | EPHX1MAPTPOLBTRPV1LMNA | |
| SCHEMBL4716481 | 0.81 | NR1D1 (0.38) | NR1D1NR1H3MAPTMEN1KMT2A | |
| SCHEMBL4716661 | 0.80 | MAPT (0.37) | EPHX1MAPTPOLBTRPV1KMT2A | |
| SCHEMBL4715548 | 0.79 | MAPT (0.37) | EPHX1MAPTPOLBTRPV1MEN1 | |
| SCHEMBL4713475 | 0.77 | MAPT (0.35) | EPHX1MAPTPOLBTRPV1MEN1 | |
| SCHEMBL4021417 | 0.75 | LIMK2 (0.39) | MAPTPOLBMEN1KMT2ALMNA | |
| SCHEMBL4016045 | 0.73 | SMN1; SMN2 (0.42) | EPHX1TRPV1MEN1KMT2ANR3C1 | |
| SCHEMBL1854854 | 0.73 | SMN1; SMN2 (0.42) | EPHX1TRPV1MEN1KMT2ANR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1986637-A1 | SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF BACTERIAL INFECTIONS | Laboratoires Serono SA (CH) | 2008-11-05 | — | — | EP | disclosed |
| WO-2007093557-A1 | SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF BACTERIAL INFECTIONS | LABORATOIRES SERONO S.A. (CH) | 2007-08-23 | — | — | WO | disclosed |