Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4715548 | 0.87 | MAPT (0.37) | MAPTEPHX1TP53TRPV1ALDH1A1 | |
| SCHEMBL4716480 | 0.82 | ALDH1A1 (0.37) | MAPTCNR1CNR2ALDH1A1HTT | |
| SCHEMBL4711906 | 0.81 | EPHX1 (0.38) | MAPTEPHX1TRPV1ALDH1A1POLB | |
| SCHEMBL4711910 | 0.79 | MAPT (0.40) | MAPTEPHX1TRPV1POLBELANE | |
| SCHEMBL4716661 | 0.79 | MAPT (0.37) | MAPTEPHX1TP53TRPV1TAS1R3 | |
| SCHEMBL4713478 | 0.77 | NR1D1 (0.38) | MAPTEPHX1TRPV1ALDH1A1GLA | |
| SCHEMBL4022922 | 0.75 | EPHX1 (0.39) | MAPTEPHX1TRPV1ALDH1A1GLA | |
| SCHEMBL4711947 | 0.72 | TSHR (0.41) | MAPTTP53ALDH1A1GLATSHR | |
| SCHEMBL4025655 | 0.70 | TSHR (0.40) | MAPTTP53ALDH1A1GLATSHR | |
| SCHEMBL4718006 | 0.70 | KMT2A (0.39) | MAPTTP53ALDH1A1GLATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1986637-A1 | SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF BACTERIAL INFECTIONS | Laboratoires Serono SA (CH) | 2008-11-05 | — | — | EP | disclosed |
| WO-2007093557-A1 | SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF BACTERIAL INFECTIONS | LABORATOIRES SERONO S.A. (CH) | 2007-08-23 | — | — | WO | disclosed |