Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4718007 | 0.79 | CSNK2A1 (0.32) | CYP1A2CYP3A4TSHRCLK4CSNK2A1 | |
| SCHEMBL4718820 | 0.77 | — | — | |
| SCHEMBL1883294 | 0.77 | TOP1 (0.39) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL5223150 | 0.73 | — | — | |
| SCHEMBL1892023 | 0.73 | F7 (0.38) | — | |
| SCHEMBL4160162 | 0.71 | — | — | |
| SCHEMBL4151460 | 0.71 | PRKD3 (0.33) | — | |
| SCHEMBL4162294 | 0.71 | — | — | |
| SCHEMBL29936937 | 0.68 | RAB9A (0.35) | CYP1A2CYP3A4TSHRCLK4CSNK2A1 | |
| SCHEMBL4927478 | 0.66 | NOS1 (0.44) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080287472-A1 | Fungicides | SYNGENTA CROP PROTECTION, INC. (US) | 2008-11-20 | — | — | US | disclosed |
| US-20080287472-A1 | Fungicides | SYNGENTA CROP PROTECTION, INC. (US) | 2008-11-20 | — | — | US | disclosed |
| US-20080287472-A1 | Fungicides | SYNGENTA CROP PROTECTION, INC. (US) | 2008-11-20 | — | — | US | disclosed |
| EP-1575949-B1 | FUNGICIDES | SYNGENTA LTD (GB) | 2008-04-02 | — | — | EP | disclosed |
| EP-1575949-B1 | FUNGICIDES | SYNGENTA LTD (GB) | 2008-04-02 | — | — | EP | disclosed |
| US-20070066605-A1 | Fungicides | SYNGENTA CROP PROTECTION, INC. | 2007-03-22 | — | — | US | disclosed |
| US-20070066605-A1 | Fungicides | SYNGENTA CROP PROTECTION, INC. | 2007-03-22 | — | — | US | disclosed |
| US-20070066605-A1 | Fungicides | SYNGENTA CROP PROTECTION, INC. | 2007-03-22 | — | — | US | disclosed |
| EP-1575949-A1 | FUNGICIDES | Syngenta Limited (GB) | 2005-09-21 | — | — | EP | disclosed |
| WO-2004056826-A1 | FUNGICIDES | SYNGENTA LIMITED (GB) | 2004-07-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080287472-A1 | Fungicides | PNPO, CYP4X1, CYP1A2 | CYP1A2 3/4885CYP3A4 12/4885TSHR 3611/4885 |
| US-20070066605-A1 | Fungicides | CYP4X1, CYP4F8, CBR3 | CYP1A2 26/4885CYP3A4 21/4885TSHR 93/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.