Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 2/20 | 0.60 |
| ▸ | GABRD | O14764 | 2/20 | 0.60 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.60 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.60 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.60 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.60 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.60 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.60 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.60 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.60 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.60 |
| ▸ | GABRE | P78334 | 2/20 | 0.60 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.60 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.60 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.60 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | GRM8 | O00222 | 1/20 | 0.54 |
| ▸ | GRM6 | O15303 | 1/20 | 0.54 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8398141 | 0.87 | GABRP (0.50) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL23420704 | 0.84 | SLC7A5 (0.46) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL5320168 | 0.84 | ALOX15 (0.56) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL1236551 | 0.84 | ALOX15 (0.56) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL27556876 | 0.84 | GABRP (0.58) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL29066564 | 0.83 | SLC7A5 (0.44) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL28226187 | 0.81 | GABRP (0.65) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL4874596 | 0.81 | GABRP (0.65) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8641185 | 0.81 | SLC7A5 (0.43) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL16774428 | 0.81 | CYP1A2 (0.53) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1537089-A4 | COMPOUNDS COMPOSITIONS AND METHODS | CYTOKINETICS INC (US) | 2008-04-16 | — | — | EP | disclosed |
| US-20080021050-A1 | Compounds, compositions, and methods | CYTOKINETICS, INC. | 2008-01-24 | — | — | US | disclosed |
| US-7211580-B2 | Compounds, compositions, and methods | CYTOKINETICS, INCORPORATED (US) | 2007-05-01 | — | — | US | disclosed |
| EP-1537089-A2 | COMPOUNDS COMPOSITIONS AND METHODS | Cytokinetics, Inc. (US) | 2005-06-08 | — | — | EP | disclosed |
| US-20040142949-A1 | Compounds, compositions, and methods | CYTOKINETICS, INC. | 2004-07-22 | — | — | US | disclosed |
| WO-2004009036-A2 | COMPOUNDS COMPOSITIONS AND METHODS | CYTOKINETICS, INC. (US) | 2004-01-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080021050-A1 | Compounds, compositions, and methods | ALPP, PCNA, MKI67 | GABRP 3271/4885GABRD 3784/4885GABRA1 4286/4885 |
| US-20040142949-A1 | Compounds, compositions, and methods | ALPP, PCNA, MKI67 | GABRP 3271/4885GABRD 3784/4885GABRA1 4286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.