Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 2/20 | 0.65 |
| ▸ | GABRD | O14764 | 2/20 | 0.65 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.65 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.65 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.65 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.65 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.65 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.65 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.65 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.65 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.65 |
| ▸ | GABRE | P78334 | 2/20 | 0.65 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.65 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.65 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.65 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | GRM8 | O00222 | 1/20 | 0.52 |
| ▸ | GRM6 | O15303 | 1/20 | 0.52 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28475312 | 0.86 | GABRP (0.54) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL28226187 | 0.85 | GABRP (0.65) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL28482072 | 0.84 | ALDH1A1 (0.60) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL14360718 | 0.84 | GABRP (0.62) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL4716019 | 0.81 | GABRP (0.60) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Chloromethane SCHEMBL29071666 | 0.81 | ALDH1A1 (0.56) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL1162283 | 0.80 | GABRP (0.65) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL18980778 | 0.80 | GABRP (0.65) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL28098659 | 0.80 | GABRP (0.65) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL28773014 | 0.79 | GABRP (0.58) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111808008-B | Biological source herbicide | 南京农业大学 | 2023-09-19 | — | — | CN | disclosed |
| US-11286234-B2 | Phenyl urea derivatives as N-formyl peptide receptor modulators | ALLERGAN, INC. (US) | 2022-03-29 | — | — | US | disclosed |
| US-20210179550-A1 | PHENYL UREA DERIVATIVES AS N-FORMYL PEPTIDE RECEPTOR MODULATORS | ALLERGAN, INC. | 2021-06-17 | — | — | US | disclosed |
| CN-111808008-A | Biological source herbicide | 南京农业大学 | 2020-10-23 | — | — | CN | disclosed |
| CN-110167921-A | ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS | 勃林格殷格翰动物保健美国公司 | 2019-08-23 | — | — | CN | disclosed |
| CN-105919987-A | N-acyloxysulfonamide And N-hydroxy-n-acylsulfonamide Derivatives And Use Thereof | 约翰斯霍普金斯大学 | 2016-09-07 | — | — | CN | disclosed |
| CN-102753520-B | N-acyloxysulfonamide and N-hydroxy-N-acylsulfonamide derivatives | 约翰斯霍普金斯大学 | 2016-06-08 | — | — | CN | disclosed |
| CN-102753519-A | Diacylated hydroxylamine derivatives | UNIV JOHNS HOPKINS | 2012-10-24 | — | — | CN | disclosed |
| CN-102753520-A | N-acyloxysulfonamide and n-hydroxy-n-acylsulfonamide derivatives | UNIV JOHNS HOPKINS | 2012-10-24 | — | — | CN | disclosed |
| CN-101305019-A | New cyclic peptide compounds | ASTELLAS PHARMA INC (JP) | 2008-11-12 | — | — | CN | disclosed |
| EP-1957518-A1 | NEW CYCLIC PEPTIDE COMPOUNDS | Astellas Pharma Inc. (JP) | 2008-08-20 | — | — | EP | disclosed |
| US-7375134-B2 | N1-(1-cyanocyclopropyl)-4-fluoro-N2-{(1S)-2,2,2-trifluoro-1-[4'-(methylsulfonyl)-1,1'-biphenyl-4-yl]ethyl}-L-leucinamide; osteoporosis and other bone loss disorders | AXYS PHARMACEUTICALS, INC. (US) | 2008-05-20 | — | — | US | disclosed |
| WO-2007049803-A1 | NEW CYCLIC PEPTIDE COMPOUNDS | ASTELLAS PHARMA INC. (JP) | 2007-05-03 | — | — | WO | disclosed |
| US-20050240023-A1 | N1-(1-cyanocyclopropyl)-4-fluoro-N2-{(1S)-2,2,2-trifluoro-1-[4'-(methylsulfonyl)-1,1'-biphenyl-4-yl]ethyl}-L-leucinamide; osteoporosis and other bone loss disorders | MERCK CANADA INC. (CA) | 2005-10-27 | — | — | US | disclosed |
| CN-1209744-A | Vitronectin receptor antagonists | SMITHKLINE BEECHAM CORP (US) | 1999-03-03 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11286234-B2 | Phenyl urea derivatives as N-formyl peptide receptor modulators | FPR1, FPR2, FPR3 | GABRP 553/4885GABRD 1641/4885GABRA1 1316/4885 |
| US-20210179550-A1 | PHENYL UREA DERIVATIVES AS N-FORMYL PEPTIDE RECEPTOR MODULATORS | FPR1, FPR2, FPR3 | GABRP 553/4885GABRD 1641/4885GABRA1 1316/4885 |
| US-20050240023-A1 | N1-(1-cyanocyclopropyl)-4-fluoro-N2-{(1S)-2,2,2-trifluoro-1-[4'-(methylsulfonyl)-1,1'-biphenyl-4-yl]ethyl}-L-leucinamide; osteoporosis and other bone loss disorders | CTSE, CTSS, CTSB | GABRP 4192/4885GABRD 4764/4885GABRA1 3710/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.