Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | IDH1 | O75874 | 2/20 | 0.37 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 5/20 | 0.34 |
| ▸ | CNR2 | P34972 | 5/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4713475 | 0.82 | MAPT (0.35) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL4712382 | 0.79 | CCR1 (0.41) | MAPTLMNAMEN1KMT2ACNR1 | |
| SCHEMBL4716481 | 0.78 | NR1D1 (0.38) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL4017082 | 0.74 | SERPINE1 (0.40) | LMNAMEN1KMT2AIDH1CNR1 | |
| SCHEMBL4711948 | 0.72 | CA1 (0.38) | MAPTCNR1CNR2CA1CA2 | |
| SCHEMBL4714206 | 0.72 | CA1 (0.44) | ALDH1A1MEN1KMT2ACA1CA2 | |
| SCHEMBL4022515 | 0.71 | CA1 (0.45) | CA1CA2 | |
| SCHEMBL4022508 | 0.71 | CA1 (0.45) | ALDH1A1MEN1KMT2AIDH1CA1 | |
| SCHEMBL4715548 | 0.69 | MAPT (0.37) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL4717985 | 0.69 | CA1 (0.47) | ALDH1A1MEN1KMT2ACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1986637-A1 | SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF BACTERIAL INFECTIONS | Laboratoires Serono SA (CH) | 2008-11-05 | — | — | EP | disclosed |
| WO-2007093557-A1 | SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF BACTERIAL INFECTIONS | LABORATOIRES SERONO S.A. (CH) | 2007-08-23 | — | — | WO | disclosed |