Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.68 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | CA6 | P23280 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | PARP1 | P09874 | 1/20 | 0.55 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.54 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11327878 | 0.85 | KDM4E (0.76) | KDM4EEGLN2ALDH1A1CA12CA1 | |
| SCHEMBL2872684 | 0.81 | KDM4E (1.00) | KDM4EEGLN2ALDH1A1CA12CA1 | |
| SCHEMBL29357844 | 0.79 | KDM4E (0.68) | KDM4EEGLN2ALDH1A1CA12CA1 | |
| SCHEMBL162859 | 0.79 | KDM4E (0.68) | KDM4EEGLN2ALDH1A1CA12CA1 | |
| SCHEMBL1363588 | 0.79 | ALDH1A1 (1.00) | KDM4EEGLN2ALDH1A1CA12CA1 | |
| SCHEMBL28853978 | 0.79 | KDM4E (0.68) | KDM4EEGLN2ALDH1A1CA12CA1 | |
| SCHEMBL27648097 | 0.79 | PKM (0.58) | CA12CA1CA2CA6CA9 | |
| SCHEMBL23484191 | 0.78 | KDM4E (0.69) | KDM4EEGLN2ALDH1A1CA12CA1 | |
| Hydrochloric Acid SCHEMBL3973558 | 0.78 | ALDH1A1 (0.96) | KDM4EEGLN2ALDH1A1CA12CA1 | |
| SCHEMBL6459633 | 0.78 | HDAC8 (0.69) | MEN1KMT2APARP1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102008459-B | Antibacterial agents | BIOTA SCIENT MAN | 2013-05-29 | — | — | CN | disclosed |
| CN-101404989-B | Antibacterial agent | PROLYSIS LTD | 2011-10-05 | — | — | CN | disclosed |
| CN-102008459-A | Antibacterial agents | PROLYSIS LTD | 2011-04-13 | — | — | CN | disclosed |
| CN-101404989-A | Antibacterial agent | PROLYSIS LTD (GB) | 2009-04-08 | — | — | CN | disclosed |
| EP-1996180-A1 | ANTIBACTERIAL AGENTS | Prolysis Limited (GB) | 2008-12-03 | — | — | EP | disclosed |
| WO-2007107758-A1 | ANTIBACTERIAL AGENTS | PROLYSIS LTD (GB) | 2007-09-27 | — | — | WO | disclosed |