Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 5/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4718889 | 1.00 | F10 (0.34) | F10P2RX7F2SOS1MCHR1 | |
| SCHEMBL4722078 | 0.90 | LIPG (0.37) | ACACB | |
| SCHEMBL4722072 | 0.90 | LIPG (0.37) | ACACB | |
| SCHEMBL14102024 | 0.90 | NOTUM (0.33) | F10F2 | |
| SCHEMBL4722513 | 0.89 | ESRRA (0.31) | — | |
| SCHEMBL4722250 | 0.85 | F10 (0.37) | F10P2RX7F2SOS1 | |
| SCHEMBL4722255 | 0.85 | F10 (0.37) | F10P2RX7F2SOS1 | |
| SCHEMBL4719016 | 0.82 | AKR1B10 (0.33) | P2RX7 | |
| SCHEMBL4724926 | 0.81 | PDE7A (0.37) | P2RX7SOS1MCHR1PDE7A | |
| SCHEMBL4724930 | 0.81 | PDE7A (0.37) | P2RX7SOS1MCHR1PDE7A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |